November 2010

Evidence of association of a common variant of the endothelial nitric oxide synthase gene (Glu298 →Asp polymorphism) to coronary artery disease in South Indian population

Genetic variants of endothelial nitric oxide synthase (eNOS) could influence individual susceptibility to coronary artery disease (CAD) with or without association with demographic factors. This study was designed to assess the Glu298 /Asp variant of the eNOS gene in 79 patients with CAD as compared to equal number (79) of controls. The genotype frequencies for eNOS gene polymorphism were determined by PCR and RFLP, and...

Author(s): Rabbani Syed, and Kaiser Jamil,

November 2010

Immunodetection of Ribin-like proteins in neuron-based cellular models

Extensive bibliographical analysis has demonstrated changes in ribin genes expression during several types of stress, especially in neurological tissues or cells during stress inducing neurological disorders. These analyses suggest that Ribin studies could be useful for neurological investigation. The present study was undertaken to detect and localize Ribin in various neuron-based cellular models mimicking...

Author(s): Roxane-Marie Barthélémy, Nadia Jaafari, Pascale Galea, Yvon Julé and Eric Faure