October 2011
Role of pyruvate dehydrogenase kinases (PDK’s) and their respective microRNA’s in human ovarian cancer
Cancer is a metabolic disorder and in energy metabolism, pyruvate dehydrogenase kinases (PDKs) play a very vital role, which make them important candidate for involvement in cancer. The bioinformatics analysis performed on ovarian cancer data sets taken from gene expression Omnibus proved the up regulation of PDK2 and PDK4. The regulating microRNA’s for these two genes were also predicted computationally, which...
October 2011
Gene mapping in a highly inbred consanguineous foveal hypoplasia family to cytogenetic region 16q24.1
A highly inbred uncle-niece, second degree consanguineous Foveal hypoplasia affected family with four members was subjected to gene mapping. Members underwent detailed ophthalmic evaluation including best corrected distance and near vision measurements, color vision assessment, fundus evaluation and flourescence angiography, horizontal corneal diameter measurement, total axial length measurement, optical coherence...
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