October 2017

Methoxy-flavones identified from Ageratum conyzoides induce capase -3 and -7 activations in Jurkat cells

New therapies for leukemia are urgently needed due to adverse side effects, tumor resistance and lack of selectivity of many chemotherapeutic agents in clinical use. Ageratum conyzoides has been used in folklore medicine for managing leukemia and other cancers. Thus, this study aimed to investigate the effects of fractions, sub-fractions and purified compounds from the ethanol leaf extracts of A. conyzoides against...

Author(s): Felix Acheampong, John Reilly, Christopher Larbie, Matthew Spencer, Karl Gunderson, Regina Appiah-Opong Christopher Howson, Jennifer Porier, Kellie Joyce, Valentina Jeliazkova, Sarah Voytek, Carol Ginsburg-Moraff, Stefan Thibodeaux, Jill Kublbeck and Steven Austin

October 2017

The antibacterial and antifungal analysis of crude extracts from the leaves and bark of Pimenta species found in Jamaica

Due to the rapid increase in the number of antibiotic-resistant bacteria, medicinal plants are being studied as new and promising alternatives to conventional antibiotic treatment. The crude hexane, ethyl acetate and methanol extracts from Pimenta dioica, Pimenta jamaicensis and Pimenta racemosa were quantitatively assessed to determine their antimicrobial susceptibility and potency using zones of inhibition methods,...

Author(s): Henry I. C. Lowe, Denise K. Daley, John Lindo, Chenee Davis, Lois Rainford, Shelly-Ann Hartley, Charah Watson, Cheryl Chambers, Glendee Reynolds-Campbell, Shadae R. Foster, Percival Bahadoosingh and Camille Thoms-Rodriguez