February 2022

Flavonoid content and antioxidant potential of leaf extracts of Passiflora setacea cv BRS Pérola do Cerrado, a new wild passion fruit cultivar

Passiflora setacea D.C. is a wild species native to the Brazilian Cerrado, with agronomic and medicinal potentials. The cultivar BRS Pérola do Cerrado is the first registered and protected cultivar of a wild Passiflora and has become an alternative to the passion fruit market due to its desirable characteristics for food, ornamental and pharmaceutic industries. Since plant tissue culture techniques are considered...

Author(s): Raphaela Santos-Tierno, Renata Garcia, Eduardo Fonseca, Fábio Faleiro, Davyson Moreira, Georgia Pacheco and Elisabeth Mansur  

February 2022

Antiplasmodial activity and phenolic composition of Brazilian Salix humboldtiana Willd. extract and fractions

Salix humboldtiana Willd. (Salicaceae) colonizes Brazilian riverine forests and, besides other congeneric species, is traditionally used to treat fever. In folk medicine, it is even used as a Quinine substitute to treat malaria fever. Although its occurrence worldwide was largely reduced between 2000-2015, in Brazil, the case numbers induced by Plasmodium falciparum have increased. Thus, new tools and strategies are...

Author(s): Ianna Dias Ribeiro Silva, Uêbem Fernandes Ramos, Luciana Esquerdo Cerqueira, Andressa Santa Brígida da Silva, Geraldo Alves Damasceno Junior, Carlos Alexandre Carollo, Ivanildes dos Santos Bastos, Patrícia Puccinelli Orlandi, Heike Markus-Michalczyk and Wagner Luiz Ramos Barbosa  

February 2022

Evaluation of the anxiolytic effects of acute administration of Passiflora alata extract in wistar rats submitted to swimming

Anxiety is present in several psychiatric disorders, and pharmacological treatment has limitations. Therefore, there is a search for new therapeutic approaches. This study aimed to evaluate the anxiolytic effect of acute administration of the dry extract of Passiflora alata (P. alata) leaves in male Wistar rats submitted to swimming. The animals were randomly divided into four groups (n = 8) (G1 to G4). G2 to G4 were...

Author(s): Airton José Mendes, Annik Ianara de Souza Greco, Renan Santiago Pereira, Wilson Roberto Malfará, Maricelma da Silva Soares de Souza, Sandra Maria Barbalho,, Elen Landgraf Guiguer, and Adriano Cressoni Araujo,  

February 2022

Antibacterial, antiquorum sensing, antibiofilm activities and chemical profiling of selected South African medicinal plants against multi-drug resistant bacteria

South African indigenous plants have been predominantly studied for their antibacterial abilities, overlooking their antipathogenic and antivirulence (also known as antiquorum sensing) potential. Hence, this study explored the selected medicinal plants as possible agents capable of interfering with bacterial growth, quorum sensing and biofilm formation and identified their respective bioactive compounds. Ten medicinal...

Author(s): Itumeleng Tsebang Baloyi, Idowu Jesulayomi Adeosun, Abdullahi Ahmed Yusuf and Sekelwa Cosa  

February 2022

Antioxidant and DNA damage protective activities of selected endophytic actinobacteria isolated from Harpagophytum procumbens: A Kalahari desert-adapted plant

Given that synthetic antioxidants are currently in use and have been demonstrated to have known negative side effects, it is important to look for natural antioxidant sources. Endophytic actinobacteria, especially those associated with medicinal plants, are one understudied source. The goal of this study was to investigate whether the secondary metabolites of endophytic actinobacteria isolated from Harpagophytum...

Author(s): Magdalena Elizabeth Lang, Timothy Sibanda, Stefan Louw and Jean Damascène Uzabakiriho