January 2011
Induction of apoptosis in MCF-7 via the Caspase pathway by longilactone from Eurycoma longifolia Jack
The effects of longilactone isolated from Eurycoma longifolia Jack were studied in human breast cancer cell line MCF-7. The research aim was to investigate the possible molecular mechanism of action of longilactone on MCF-7. The SRB assay showed that longilactone exerts a strong cytotoxic activity on MCF-7 with an IC50 of 0.53 ± 0.19 µg/ml. Hoechst 33342 staining assay and TEM analysis...
January 2011
Pharmacognostic evaluation of the Amaranthus viridis L.
The Amaranthus viridis Linn. (Family Amaranthaceae) plant was studied to determine the various parameters for pharmacognostical standards. The present investigation deals with the report on macro and microscopical, vein islet and vein termination numbers, palisade ratio, stomatal index (upper and lower surfaces of the leaf) and different chemical parameters have been determined. These findings will...
