International Journal of
Biotechnology and Molecular Biology Research

  • Abbreviation: Int. J. Biotechnol. Mol. Biol. Res.
  • Language: English
  • ISSN: 2141-2154
  • DOI: 10.5897/IJBMBR
  • Start Year: 2010

IJBMBR Articles in press

Gene Regulating Effects of Cymbopogon citratus on Glucose Metabolism of Normal Albino Rats

Article in Press

Cymbopogon citratus has been reported to have hypoglycaemic and antidiabetic activities. This study evaluated the insulinotropic properties of C. citratus via gene expression. C. citratus was administered to normal rats as pulverized leaves (2%, 10% and 30%) mixed with animal feed for one week; as aqueous and ethanol extracts at a dosage of 30 and 100mg/kg body weight for 30 days; and as isolated saponins, flavonoids and...

Author(s):Adegbegi Ademuyiwa Joshua, Onoagbe Iyere Osalase, Omonkhua Akhere Akuekegbe

Rilpivirine and Etravirine Resistance Among HIV-1 Infected Patients Failing First Generation NNRTIs in Busia, Western Kenya

Article in Press

Introduction: Rilpivirine (RPV) and Etravirine (ETR) are second-generation non-nucleoside reverse transcriptase inhibitors (NNRTIs) that are not used for HIV-1 treatment in Kenya. In this cross-sectional study, we analyzed the reverse transcriptase region of HIV-1 from 140 HIV-1 infected individuals from Busia County Referral Hospital, Busia County, Kenya, who were on treatment with confirmed virologic failure. Methods:...

Author(s):James Munyao Kingoo, Anne WT Muigai, Viviene Matiru, Samoel A. Khamadi

Cold tolerance and amino acid content of overwintering eggs in Gomphocerus sibiricus L. (Orthoptera: Acrididae)

Article in Press

This study investigated the changes in cold tolerance capacity and amino acid content in the eggs of Gomphocerus sibiricus. The super-cooling points (SCPs) and freezing points of G. sibiricus eggs were measured monthly using thermocouples. The water content was determined via oven-drying, and the amino acid content was measured with an amino acid automatic analyser. The SCPs of G. sibiricus eggs initially increased and...

Author(s):Ye Xiao-Fang, He Li-Zhi, Wang Xiang-Xiang, Yan Meng-Yun, Wang Han, Yu Fei, Yuan Liang, Hu Hong-Xia, He Lan, Chen Xiao, Li Zhan-Wu, Ji Rong

Extraction, Isolation and Characterization of Pure Compounds from Prosopis juliflora, and Determination of the Effects of the Compounds on Groundnut Aphids

Article in Press

Natural products from medicinal plants, either as pure compounds or as standardized extracts, provide unlimited opportunities for different purposes. Botanical preparations of medicinal plants for insecticidal usage contain various types of bioactive compounds. The focus of this paper is the botanical evaluation of stem bark, seed and leaf extracts of Prosopis juliflora for their insecticidal effect against groundnut...

Author(s):Mulate Zerihun, Estifanos Ele

Forward genetics in smut fungi: Creation of mating defective mutants of Sporisorium scitamineum for gene discovery

Article in Press

Sexual phases among pathogenic fungi are major determinants of morphological transitions linked to virulence. The sugarcane smut fungi, Sporisorium scitamineum, are an obligate bitrophic pathogen, whose molecular basis of sexual mating is poorly understood. Here we report the creation of a library of mating-defective mutants of S. scitamineum using Agrobacterium mediated random insertional mutagenesis in the quest to...

Author(s):Tinashe Josiah Runyanga, Yubin Chen and Fei Sun

Effect of 2, 4-dichlorophenoxy acetic acid and naphthelene acetic acid concentrations on callogenesis for in vitro regeneration in selected sugarcane varieties

Article in Press

This study investigated the effect of 2,4-dichlorophenoxyacetic acid (2, 4-D) and naphthalene-1-acetic acid (NAA) concentrations on callus induction and shoot regeneration in three sugarcane varieties: CO945, CO421, and N14. Young leaf spindle explants were cultured on Murashige and Skoog (MS) basal medium supplemented with 2, 4-D (0.0, 2.0, 2.5, 3.0, 3.5 and 4.0 mg L-1) and NAA (0.0 and 1.0 mg L-1). Experiments were laid...

Author(s):RICHARD WEKESA, Justus Onguso, Bernard Nyende, Leonard Wamocho

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