African Journal of
Pure and Applied Chemistry

  • Abbreviation: Afr. J. Pure Appl. Chem.
  • Language: English
  • ISSN: 1996-0840
  • DOI: 10.5897/AJPAC
  • Start Year: 2007
  • Published Articles: 363

AJPAC Articles

Physico-chemical analysis and toxicological studies of Madaran sukudai (a local drink in Northern Nigeria)

June 2008

Physico-chemical analyses have been carried out on concentrated Madaran sukudai, diluted M. sukudai and pure formalin. Both the infrared and UV-visible spectroscopic studies on the three solutions revealed that the madaran sukudai is essentially a dilute formalin solution. Toxicological studies of the effect of M. sukudai on the white albino rats were also carried out. The results showed that there was significant...

Author(s): Owalude, S. O. and Tella, A. C.

Effect of intraperitoneal administration of vitamin C (ascorbic acid) on anemia in experimental Trypanosoma congolense infected rabbits

April 2008

The effect of Vitamin C supplementation on anemia in experimental Trypanosoma congolense infected rabbits was investigated. Locally bred rabbits were infected with 6 ´ 106 trypanosomes per rabbit and infection was monitored for 5 weeks. Packed cell volume (PCV), Total leucocytes count (TLC) and parasite load were determined weekly. Vitamin C supplementation did not significantly affect...

Author(s): Toma, I, Shinggu, D. Y, Ezekiel, W and Barminas, J. T

Miscibility studies of PVC/PMMA and PS/PMMA blends by dilute solution viscometry and FTIR

April 2008

The effect of polymer-polymer interactions on the miscibility of PVC/PMMA and PS/PMMA blends were studied in a broad composition range using viscosity and FTIR techniques. From the viscometric data, the presence of attractive forces among different polymers was evaluated according to Sun et al. (1990), by the determination of α parameter. Based on sign convention involved in the criterion, PS/PMMA system was...

Author(s): Mohammad Saleem Khan, Raina Aman Qazi and Mian Said Wahid.

Nanotechnology importance in the pharmaceutical industry

March 2008

During the last decades, pharmaceutical technology has taken the advantage of the advent of nanotechnology and, now days, new pharmaceutical dosage forms are under development to deliver many physicochemically different drug molecules. The present study is to investigate the role and their importance of nanotechnology in the pharmaceutical development.   Key words: Nanotechnology, drug delivery,...

Author(s): Ramesh Reddy Putheti, R N Okigbo, Madhusoodhan Sai advanapu and Sangeeta Chavanpatil

Application of grafted membranes for sorption of Cd2+, Fe2+ and Zn2+ ions in aqueous solution

March 2008

Sorption of  Cd2+, Fe2+ and Zn2+ by blend membrane of sodium alginate (Na-Alg) and poly (acrylamide) grafted konkoli gum (KG-g-PAAM) in aqueous solution was studied.  Membrane sorption capacities for Cd2+, Fe2+ and Zn2+were found to be 97.85, 80.65 and 64.46% respectively. The sorption behavior with respect to contact time, initial pH, temperature, ionic strength and initial metal ion...

Author(s): S. A. Osemeahon, Barminas, J. T, Aliyu, B. A and Nkafamiya, I. I.

Development and validation of LC method for the determination of leflunomide in pharmaceutical formulations using an experimental design

February 2008

A rapid and sensitive RP-HPLC method with UV detection (260 nm) for routine analysis of leflunomide in a pharmaceutical formulation was developed. Chromatography was performed with mobile phase containing a mixture of acetonitrile and phosphate buffer (60:40, v/v) with flow rate of 0.8 ml min−1. Quantitation was accomplished with internal standard method.  The procedure was validated for linearity...

Author(s): Srinivas Rao V, Sunanda K. K, Narasimha Rao M., Allam Appa Rao, Maheswari IL and Srinubabu G

Enhancing trends of intensity signal of trace level Hf in zirconium oxide using AES sequential addition method

February 2008

A sensitive, rapid and simple method to detect Hf at trace level in Zr has been described. It is based on the sequential addition of sample after each pre excitation period, in presence of graphite as buffer. The improvement with respect to the other published procedures lies in the use of solid powdered sample, omitting the step of wet chemistry or use of any optical filter. The enhancing trends of intensity curves...

Author(s): Ishrat Rehana and Saeed Ahmed

Chromatographic method development: computer simulated statistical design approach

January 2008

The computerization of method development and validation are useful in analysis of pharmaceuticals in pharmaceutical industry. In this article a simple and rapid high performance liquid chromatographic method has been developed for the determination of oxcarbazipine in pharmaceutical formulations. Factorial design was applied for optimization of essential factors for robustness study. A linear model was postulated and a...

Author(s): Allam Appa Rao

Study on QSPR method for theoretical calculation of heat of formation for some organic compounds

January 2008

Quantitative Structure – Property Relationship (QSPR) models based on molecular descriptors derived from molecular structures have been used for the prediction of heat of formation using a set of 20 organic compounds. The molecular and quantum chemical descriptors used to represent molecular structure include topological indices and constitutional descriptors. Forward stepwise regression was used to...

Author(s): Ashrafi Ferydoun, Rostami Abbas Ali and Mahdavipour Najmeh

Contribution from the employment of volcanic tuffs to the chemistry of soda- lime glasses

November 2007

The present work shows a study to incorporate volcanic tuffs as raw material in the preparation of industrial glass that traditionally uses feldspar. The X- ray diffraction patterns obtained with hot camera depict an unstable mineralogical phase under special conditions of atmospheric pressure in which appears the quartz polymorphic transformation. Thermal analysis curves present a shoulder at 680oC and an endothermic...

Author(s): Rafael Jordán Hernández, Tania Faría Piñera, Gerardo Rodríguez- Fuentes, Gerardo C. Díaz Trujillo and María E. Zayas Saucedo

Chemical oxides analysis from Azara Baryte

November 2007

Physical and chemical analysis of the two samples A and B of Azara baryte were conducted, such as moisture content, loss on ignition and elemental composition by the use of atomic absorption spectrophotometer(ASS) and flame photometer. The oxides values in 1.000 g sample of each element were obtained. Sample A (lower layer): moisture content = 0.020, loss on ignition = 0.060, Na2O = 0.250, K2O = 0.015, CaO = 0.014, MgO...

Author(s): Hauwa Isa

omputational approach of protein analysis using affinity chromatography: application to proteomics

September 2007

Computerization is necessary to build the database of chromatography coupled mass spectrometric analytical data. On the basis of this proteomic data we can identify the proteins as biomarkers which are expressing dissimilarity between healthy and disease condition. Affinity chromatography is one of the fastest liquid chromato-graphic methods for the separation and purification of biomolecules due to its high molecular...

Author(s): Allam Appa Rao

Tetrapropylammonium bromochromate and tetrabutylammonium bromochromate [NR4]CrO3Br, (R= Pr, Bu): two new and efficient reagents for oxidation of alcohols

September 2007

Tetrapropylammonium bromochromate (VI), [N(Pr)4]CrO3Br, TPABC and tetrabutyl-ammonium bromochromate (VI), [N(Bu)4]CrO3Br, TBABC were prepared and used to quantitatively oxidizing of a number of organic substrates. These reagents are versatile reagents for the effective and selective oxidation of organic substrates, in particular for alcohols, under mild conditions.   Key...

Author(s): Shahriare Ghammamy, Kheyrollah Mehrani, Hamid Afrand and Maryam Hajighahramani

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