Journal of
Metabolomics and Systems Biology

  • Abbreviation: J. Metabolomics Syst. Biol.
  • Language: English
  • ISSN: 2805-4210
  • DOI: 10.5897/JMSB
  • Start Year: 2010
  • Published Articles: 10

JMSB Articles

Metabolite profiling of different solvent extracts of Moringa oleifera seeds and correlation with DPPH radical scavenging activity via 1H NMR-based metabolomics

September 2023

In the present study, profiling of the Moringa oleifera seeds metabolome was carried out by employing proton nuclear magnetic resonance (1H NMR) spectroscopy combined with multivariate data analysis (MVDA) of 3 different solvent extracts. The principal component analysis (PCA) and partial least square-discriminant analysis (PLS-DA) score plot reveal that methanol extract was discriminated from ethyl acetate and hexane...

Author(s): Famurewa Oluwayemisi Juliannah, Istifanus Yarkasuwa Chindo and Auwal Adamu Mahmoud

Taurine is a future biomolecule for potential health benefits: A review

September 2022

Taurine is a sulfur-containing amino acid that is converted to a neutral beta-amino acid, chemically known as (2-Amino-ethane sulfonic acid) having chemical formula C2H7NO3S. It was first isolated from Ox bile, and thus derives its name from the Latin word “Taurus”, meaning 'ox' or 'bull'. This is the only amino acid that is extensively found in animal tissue. The richest source of taurine is...

Author(s): Rajeshwar Nath Srivastava, Zeenat Ara, Shah Waliullah, Alka Singh,  Saloni Raj, Abbas Ali Mahdi, Ravindra Kumar Garg, and Raja Roy

1H NMR urine metabolomics is an effective prognostic indicator in acute spinal cord injury (ASCI): A prospective case-control study

October 2020

Acute spinal cord injury (ASCI) is an extremely overwhelming disease with high morbidity and mortality. Despite significant successes in understanding the pathophysiology of ASCI, little is known about limiting neurological damage and predicting recovery. Biofluid metabolomics by 1H NMR spectroscopy for metabolites quantification specific to nervous tissue injury may determine the injury and progression. This study...

Author(s): Alka Singh, Rajeshwar Nath Srivastava, Tanushri Chatterji, Suruchi Singh, Lavini Raj, Abbas Ali Mahdi, Ravindra Kumar Garg and Raja Roy  

Virtual environments for mental health issues: A review

April 2014

Three-dimensional (3D) environments are increasingly being used to provide therapy to those suffering from mental health problems. Virtual environments can provide a safe and realistic simulation to expose patients to the cause of their problem. This paper presents a review of the use of 3D environments to assess and treat mental health problems. Within the review applications to treat mental health problems such as...

Author(s): David Haniff, Alan Chamberlain, Louise Moody and Sara De Freitas  

Conception of biological networks at the molecular level as orchestrated systems of oscillators representing interconnected modular molecular clocks

September 2011

Biological networks are extremely complex objects. Still representation of them remains to be very simple. Here hypothesis representing all regulatory cellular processes as cycles connected to each other is provided. Cycles were introduced as minimal parts of network containing negative feedback loop. All cycles were interconnected between each other by common members of network; it can be gene, protein or metabolite....

Author(s): Alexander A. Belostotsky

Metabolite profiling of endophytic fungal isolates of five ethno-pharmacologically important plants of Meghalaya, India

September 2011

Crude metabolite extracts derived from the culture broths of endophytic fungi of five ethno-pharmacologically important plant species used by the ethnic tribes of the hill state of Meghalaya in North-East India were screened for the presence of toxins and secondary metabolites using agar plug paper chromatography, TLC (thin layer chromatography) and LC-MS (liquid chromatography-mass spectroscopy). The endophytic fungal...

Author(s): R. K. Bhagobaty, and S. R. Joshi

Urinary metabolic profiling in rats due to heat exposure using 1H high resolution NMR spectroscopy

April 2011

Acute heat stress may trigger systemic biochemical and physiological changes in living organisms leading to rapid loss of homeostasis. Metabolic regulatory process during heat stress has been poorly understood therefore the present study was undertaken in order to have an insight of alterations in various metabolites due to acute heat stress exposure using nuclear magnetic resonance (NMR) spectroscopy. Male...

Author(s): Sonia Gandhi, M. Memita Devi, Poonam Rana, Sunil Pal, Rajendra P. tripathiand Subash Khushu

Determination and detoxification of cyanide content in sorghum for ethanol production using Saccharomyces cerevisiae strain

April 2011

Sorghum is a promising crop for the animal feed and fuel ethanol production. Presence of cyanide in its biomass, particularly in the tips of young leaves, carries some risk of toxicity to livestock and microbes, especially when at an immature stage of growth, its application may be restricted. The study was carried out at Indian Agricultural Research Institute, New Delhi with nine forage sorghum cultivars to determine...

Author(s): S. Prasad and M. S. Dhanya

Prevalence of (high-pathogenicity island) HPI-harboring Escherichia coli in diarrheic and healthy piglets

August 2010

One hundred and sixty four rectal swab samples were collected from 110 live diarrheic piglets and 54 healthy piglets during an investigation on the prevalence of HPI-harboring Escherichia coli (HPI + E. coli) infection associated with porcine diarrhea. The data of polymerase chain reaction (PCR) revealed the presence of HPI + E. coli in 58.18% of swabs taken from...

Author(s): DaRong Cheng, XiaoLang Chen, ShanYuan Zhu, WenWei Ding, ZhiXia Mu and Jun Zhou,

Effect of dehydration on the nutritive value of drumstick leaves

August 2010

Food based strategy’ is used as a tool for combating micronutrient deficiencies. It is also referred as dietary modification, which encompasses a wide variety of intervention that aim at increasing the production, availability and consumption of food products, which are rich in micronutrients. One such food products are green leafy vegetables. There are many varieties of green leafy vegetables which...

Author(s): Pallavi Joshi and Dipika Mehta

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