December 2010

Correlation between moderate Plasmodium falciparum malarial parasitaemia and antioxidant vitamins in serum of infected children in South Eastern Nigeria

The levels of antioxidant vitamins were estimated in Plasmodium falciparum malarial infected children aged 0 to 12 years. 113 children with P. falciparum infection were selected based on laboratory evidence and clinical symptoms. 87 apparently healthy children with no malarial parasitaemia were included as the control subjects. P. falciparum parasitaemia and serum levels of antioxidant...

Author(s): I. Onyesom, R. C. Ekeanyanwu and N. Achuka

December 2010

The use of cholinergic biomarker, cholinesterase activity of blue mussel Mytilus edulis to detect the effects of organophosphorous pesticides

The aim of the study was to investigate the effects of organophosphorous pesticide on thecholinesterase activity of different organs of Mytilus edulis. The mussels were exposed to serial dilutions of the pesticides (0, 50, 100, 200, 500, and 1000 µg/l) for 96 h. A significant inhibition of the cholinesterase activity from gill occurred at the lowest concentration, which indicated that gill was the...

Author(s): K. Yaqin and P. D. Hansen

December 2010

Biochemical profile of sodium selenite on chemically induced hepatocarcinogenesis in male Sprague-Dawley rats

Despite the success of experimental, clinical and epidemiological studies on selenium as an anti-cancer agent, basic studies on the effects of selenium are still scanty. This study was designed to investigate the biochemical effects of sodium selenite using preventive and therapeutic approaches on chemically induced hepatocarcinogenesis in rats. Rats were divided randomly into 6 groups: negative control, positive...

Author(s): Nasar Yousuf Alwahaibi, Siti Belkis Budin and Jamaludin Mohamed