December 2014

Evaluation of anti-inflammatory and antinociceptive activities of the Austroplenckia populnea extract in topical formulations

Austroplenckia populnea (Reiss.) Lundell is a Brazilian Cerrado plant that has been widely used in folk medicine and has many therapeutic properties. The aim of this study is to evaluate the anti-inflammatory and antinociceptive properties of a raw hydroalcoholic wood extract of A. populnea in semi-solid formulations administered topically in rats. The extract of A. populnea was administrated topically in male and...

Author(s): Larissa Dias Menezes, Gúbio Oliveira Gomes, José Antônio Paixão da Silva Neto, Mariana Laundry de Mesquita, Vania Moraes Ferreira and Mônica Valero da Silva  

December 2014

Potency and immunogenicity of bacillus calmette guerin (BCG) vaccines used in routine immunization programme in South-East, Nigeria

The efficacy of every vaccine depends in part on appropriate vaccine handling from the manufacturer to its utilization. There is need for continuous monitoring of vaccine to ensure that cold-chain system is maintained throughout the product life-span. This study aims to validate the BCG vaccines used in immunization in South-East, Nigeria. The potency of the vaccines was determined by viable count on...

Author(s): Oli, A. N., Agu, R. U., Nnadozie, O. J., Onah, C. E., Okeke, I. J. and Esimone, C. O.  

December 2014

Assessment of highly active antiretroviral therapy (HAART) adherence among HIV patients in a tertiary health institution in Nigeria

The introduction of highly active antiretroviral therapy (HAART) in the management of HIV lead to a substancial decline in human immunodeficiency virus (HIV) mortality. However, the optimization of patients response to this therapy is highly dependent on medication adherence. The objective of this study is to identify the determinants of adherence to HAART and HIV/AIDS patients’ adherence in a selected HIV clinic....

Author(s): Nwankwo U. Victoria, Nduka O. Sunday, Ilodigwe E. Emmanuel, Ogbonna Brian, Uzodinma U. Samuel and Okonta J. Matthew

December 2014

Aphrodisiac properties of Tynanthus micranthus Corr. & Mello ex. Schum in male mice

In traditional medicine, a variety of plants have been used as sexual stimulants. Within the genus Tynanthus (Bignoniaceae) some species are known by their aphrodisiac effects, including Tynanthus micranthus Corr. & Mello ex. Schum. The purpose of this study was to evaluate the sexual behavior of male mice treated with a crude extract of the aerial parts (leaves and stems) of T. micranthus, for this, the extracts...

Author(s): Fernanda Colombi Cansian, Francis José Zortéa Merino, Vera Lucia Lângaro Amaral, Rafael Alonso Salvador, Patrícia Mazureki Campos, Deise Prehs Montrucchio, Obdulio Gomes Miguel and Marilis Dallarmi Miguel