April 2014
Comparative pharmacokinetic study of luteolin after oral administration of Chinese herb compound prescription JiMaiTong in spontaneous hypertensive rats (SHR) and Sprague Dawley (SD) rats
JiMaiTong (JMT), a Chinese herb compound prescription consisted of Flos chrysanthemi Indici, Spica prunellae and Semen cassiae for anti-hypertension. Luteolin is one of the major bioactivity compositions in F. chrysanthemi Indici in JMT. There are some reports about pharmacokinetics of luteolin in extract of F. chrysanthemi and husks of peanut in normal rats, but it lacked pharmacokinetic information of luteolin...
April 2014
Effect of Thespesia populnea Linn. on dexamethasone induced insulin resistance in mice
In traditional medicine, plants have been used to treat diabetes mellitus as valuable alternative therapy since synthetic oral hypoglycemic agents are known to exhibit adverse side effects. The present study was planned to investigate the effect of ethanolic extract of bark of Thespesia populnea Linn (TP) on plasma glucose, serum triglyceride and body weight in dexamethasone-induced insulin resistance in mice. The...
April 2014
Clinical and microbiological effects of systemic ciprofloxacin and metronidazole in Aggregatibacter actinomycetemcomitans-associated periodontitis
Destructive periodontal disease is a concern because of the potential damage to the dentition and the financial burden of treatment. It is generally agreed that the microorganisms residing in periodontal pockets are responsible for periodontitis. Approximately 500 bacterial taxa inhabit periodontal pockets. Association between Aggregatibacter actinomycetemcomitans and destructive and progressive forms of periodontitis...
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