March 2016

Anticonvulsant and anxiolytic activity of the leaf aqueous and ethanolic extracts of Melanthera scandens in a rat model

Modern drug therapy of epilepsy is complicated by the inability of drugs to control seizures in some patients and side effects that range in severity from minimal impairment of the central nervous system to death from aplastic anemia or hepatic failure. Medicinal plants used in traditional medicine for the treatment of epilepsy have been scientifically shown to possess promising anticonvulsant activities in animal...

Author(s): Silvano S. Twinomujuni , Joseph Oloro and Paul E. Alele

March 2016

Effects of Hibiscus rosa-sinensis leaf products on haematological indices, lipid profile and hepatic parameters of hyperlipidemic rat

Previously, we demonstrated that Hibiscus rosa-sinensis leaf contains various secondary metabolites including saponins, tannins and oxalates, which are known to possess documented pharmacological activities. In this present study, we investigated the effects of the leaf products on haematological indices, lipid profile and hepatic parameters using Wistar albino rat bioassay. Data suggested that though the haemoglobin...

Author(s): Don Daniel Nwibo, Mirabel Ifeyinwa Eze  and Thomas Mmuoemene Okonkwo

March 2016

Evaluation of the compliance of women with breast cancer to treatment in a reference hospital in a city of North-east, Brazil

For the translation, transcultural adaptation and a pilot test of the instrument were done. Also, the compliance of the breast cancer patients to the treatment was measured. The questionnaire “Cancer Patient Self-Report Questionnaire Non-Adherence” was translated and adapted; and a pilot test with 30 patients was performed. For this study, the questionnaire, Morisky-Green test, was also used. A hundred and...

Author(s): Anderson L. Freitas, Wellington B. da Silva, Aline de J. Santos, Wesley M. dos Santos and Allan J. de O. Melo

March 2016

Evaluation of clinical parameters in people living with HIV undergoing pharmacotherapeutic monitoring: Viral load, CD4+ T lymphocytes and adherence to antiretrovirals

The aim of this study was to evaluate the clinical indicators (viral load- VL, CD4 lymphocytes and adherence) of HIV+ patients, at the beginning of treatment with antiretrovirals (ARV), during pharmacotherapeutic monitoring (PTM) in a specialized center in Fortaleza, Ceará. The longitudinal study, according to the Dáder method, was used for patients with HIV (n = 100) from 2008 to 2012, beginning at the...

Author(s): Henry Pablo L. C. Reis, Darlan da S. Cândido, Catarine V. Loureiro, Juliana de O.Carlos, Ana Maria S. de Araújo, Maria Jacqueline Batista and Marta Maria de F. Fonteles,