October 2016
Analgesic and central nervous system depressant activities of methanol extract of Ziziphus rugosa Lam. Leaves
The present investigation was designed to evaluate the analgesic and central nervous system (CNS) depressant activities of the methanolic extract of Ziziphus rugosa Lam. in rat model. The analgesic activity of the extract was examined using acetic acid-induced writhing test (chemically induced pain) at the doses of 200 and 300 mg/kg body weight. Further, the CNS depressant activity of the plant extract was evaluated by...
October 2016
Development of nano particle encapsulated pemulen gel for aceclofenac topical delivery
Management of rheumatic disorders are limited by the inability to provide long-term drug delivery due to the irritation to gastric mucosa and poor availability of drugs, which may be overcome by prolonging the drug release. The nanostructured carriers (NP)based gel was developed as potential topical system for aceclofenac topical delivery. In the present study, chitosan-sodium alginate...
Advertisement
Advertisement