August 2014

In vitro and in vivo protective action of ethanolic extract of Triphala on LDL against glycation-oxidation

The modified low-density lipoprotein (LDL; glycated and oxidized) is more atherogenic and are poorly recognized by LDL receptor. In the present study, an attempt has been made to evaluate the effects of Triphala on LDL modification in experimentally treated rats and in human LDL. The effect of ethanolic extract of Triphala on LDL oxidation susceptibility in high fat diet fed and STZ induced rats was evaluated. The...

Author(s): Babu Deepa, Prema Gurumurthy,Sai Krishna Borra and K. M. Cherian

August 2014

Antidepressant-like effects of flavonoids extracted from Apocynum venetum leaves in mice: the involvement of monoaminergic system in mice

The present study investigated a possible antidepressant-like activity of flavonoids extracted from Apocynum venetum leaves using two predictive tests for antidepressant effect on rodents: the forced swimming test (FST) and the tail suspension test (TST). Additionally, the monoaminergic mechanisms involved in the antidepressant-like effect of AV-extract in the mouse forced swimming test (FST) were evaluated. The extract...

Author(s): Meizhu Zheng, Yuqiu Li, Dongfang Shi, Chunming Liu and Jimin Zhao