August 2016
Eye drops prescription pattern in patients with glaucoma
Glaucoma is a major public health problem, being the leading cause of irreversible visual impairment worldwide. In most cases, glaucoma is associated with intraocular pressure (IOP) levels that are above those considered normal (IOP ≥ 21 mmHg). The aim of the present work is to describe the pattern of eye drops prescription in patients with glaucoma in the state of Sergipe, Brazil. A descriptive cross-sectional study...
August 2016
Preclinical evaluation of repeated dose toxicity and anxiolytic activity of monoterpene R - (+) – limonene via inhalation
R - (+) - limonene is a monoterpene found in several plant species. Studies have shown that plants that have this compound has anxiolytic activity. This study aimed to investigate the anxiolytic and toxicological activity in rats after inhalation of R - (+) - limonene for 30 min. For the anxiety tests using Elevated Plus Maze (EPM), concentrations of 1.0, 2.5 and 5.0% were determined. From the results, it was observed...
August 2016
Toxicogenetic biomonitoring of workers to the ionizing radiation
Occupational exposure to ionizing radiation (IR) can cause systemic acute and chronic effects on human health, including genetic instability that may be etiology of various diseases, including cancer. The aim of this study was to evaluate the possible toxicogenetic changes in haematological and biochemical parameters, and cytogenetic biomarkers (micronuclei and nuclear abnormalities) indicators of mutagenicity and...
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