November 2015

Assessment of Cassia siamea stem bark extracts toxicity and stability in time of aqueous extract analgesic activity

Cassia siamea Lam (Fabaceae), widely used in tropical countries for its nutritional and pharmacological properties, has been toxicologically evaluated. Oral administration of aqueous (CSE4) and ethanol (CSE3) Cassia siamea stem bark extracts did not show mortality up to 3000 mg/kg in albinos Wistar rats. LD 50 of petroleum ether (CSE1) and dichloromethane (CSE2) extracts were estimated at 1300 and 1275 mg/kg...

Author(s): Nsonde Ntandou G. F.,,  Bassoueka D. J., Banzouzi J. T. , Etou Ossibi A. W., Elion Itou R. D. G., Makambila M. C., Ramos S., Benoit-Vical F., Abena A. A. and Ouamba J. M.

November 2015

Evaluation of neuropharmacological, analgesic and anti-inflammatory effects of the extract of Centella asiatica (Gotu kola) in mice

Continued research on traditional herbal drugs has become important than ever due to their increasing use and demand as food supplements and nutraceuticals. The standardized extract of Centella asiatia (L.) Urban (Apiaceae), commonly known as Gotu kola, was evaluated for neuropharmacological, analgesic and anti-inflammatory effects. Neuropharmacological activities were performed on specifically design apparatus, whereas...

Author(s): Mahmood Qureshi, Mehjabeen, Noor Jahan, Shafi Muhammad, Nadeem Mohani, Asma Wazir, Iftikhar Ahmed Baig and Mansoor Ahmad