October 2015

Antimicrobial properties of the methanol leaf extract of Vernonia glaberrima Welw. Ex O. Hoffm (Asteraceae)

The emergence of multi-drug resistant microbes necessitates a continuous search for newer, effective antimicrobial agents. The crude methanol leaf extract of Vernonia glaberrima was screened for its antimicrobial activity against pathogenic microorganisms including Methicillin resistant Staphylococcus aureus, Vancomycin resistant enterococci, Listeria monocytogenes, Staphylococcusau reus, Helicobacter pylori,...

Author(s): Abdullahi, M. I., Uba, A., Alebiosu, C. O.,  Alhassan, A. M. , Mode, S., A. Umar , Nasir,  I., S. S. Bello, Ibrahim, Z. Y. Y., Yunusa, A. and Yusuf, A. J.

October 2015

Camellia sinensis extract inhibits in vitro pancreatic lipase and has preventive effect on obesity in female rat fed a high-fat diet

The aim of this study was to evaluate eight plants extract for porcine pancreatic lipase inhibition, characterizing biochemically the extract with high inhibitory activity and its effects on preventing weight gain in female rat fed a high-fat diet (HFD). In vitro pancreatic lipase inhibition was carried out in ρ-nitrophenyl-laurate substrates and a double-reciprocal plot was used for inhibition mechanism...

Author(s): Erika Carolina Vieira-Almeida, Acácio Antonio Pigoso and Alex Fernando de Almeida

October 2015

Anti-bacterial and anti-inflammatory effects of Tanshinone breast filler in mice

The purpose of this study was to investigate the antibacterial and anti-inflammatory activities of Tanshinone breast filler (TBF) against cow mastitis. TBF on bacterial activity in vitro by the method of Oxford cup and the mice were treated by TBF before given the mixed bacterial by intraperitoneal injection in vivo. The effect of TBF against acute inflammation was studied by xylene-induced ear edema and egg...

Author(s): Wenchu Ye, Yun Ban, Fuwei Yuan, Limei Dang, Xianhui Xu, Ruijiao Zhao, Jie Zhang, Fan Zhang, Yinqian Li

October 2015

In-vivo antiplasmodial activity of methanol whole plant extracts of Tapinanthus dodoneifolius (DC) Danser in mice

Aqueous preparations of the whole plant of Tapinanthus dodoneifolius (DC) Danser growing on Parkia biglobosa tree are used by the nomads in Northern part of Nigeria for managing malaria, and many other ailments example, diabetes, fever, diarrhoea and wounds. To date, there are no efficacy or safety studies carried out to support its ethno-medicinal use in malaria management. This study aims to investigate the...

Author(s): Z. Abdullahi, J. A. Anuka, A. O. Salawu and I. M. Hussaini