September 2017

Anti-inflammatory and non ulcerogenic activities of acetylbergenin

Endopleura uchi (Huber) Cuatrec. (Humiriaceae), the Brazilian Amazon plant, is used in folk medicine to treat arthritis and gastric ulcer. Bergenin, one of the chemical constituents of E. uchi, has anti-inflammatory properties. Its acetylation results in acetylbergenin, which is extracted to investigate its potential anti-inflammatory and antiulcer properties using an assay for croton oil-induced ear edema, rat paw...

Author(s): Jaqueline C. Moreira Borges, Raimundo W. de Sousa Aguiar, José F. de Sousa, Haroldo S. Ripardo Filho, Giselle S. Pinheiro Guilhom, Lourivaldo S. Santos, Pergentino J. Cunha Sousa, Bruno G. Pinheiro, Hugo A. S. Favacho and Jose C. Tavares Carvalho

September 2017

Phytochemical screening and toxicity profiles of crude extracts of Cissus quadrangularis L. and Solunum incanum L. in mice

Plant derived bioactive molecules are always in demand and are the main focus of research. Despite the growing market demand for herbal medicines, safety of medicinal plants is still a concern. The present work aimed at generating preliminary phytochemical and biosafety information of crude methanolic and chloroform extracts of Cissus quadrangularis L. (aerial parts) and Solunumincanum L. (fruit). Both plants are...

Author(s): Teka Feyera, Solomon Assefa, Endalkachew Mekonnen and Abi Legesse