Cassava (Manihot esculenta) remains an important root crop that is consumed by more than 400 million people in the world. It is an important source of starch products and animal feeds. The crop has high a yield potential, can withstand pests and disease attack and harsh weather conditions and grows well even on poor soils throughout the year. Despite its importance, cassava is mainly grown for subsistence use especially in sub-Saharan Africa. This study investigated cassava commercialization and its determinants in Busia County among 60 randomly selected cassava farmers. Data was collected using a questionnaire and interview schedule. The descriptive and multi-linear regression results indicated that cassava commercialization index was 53.79%. Commercialization was influenced by gender and age of the farmer, distance to seed and nearest market, experience, quantity of cassava sold, price, credit access, total land in acres, maturity period, machine and labor and varieties of cassava. Generally, poor market, diseases, lack of credit and market information affected cassava farming. Thus measures that will enhance farmers` capacity to commercialize cassava such as access to improved cassava seed varieties, improved farmers` skills and knowledge on appropriate cassava agronomic practices, and access to cassava input and output markets are recommended.

Keywords: Cassava, commercialization, determinants, constraints