July 2012

Genotypic diversity and mutation profile of HIV-1 strains in antiretroviral treatment (ART) -Naïve Ghanaian patients and implications for antiretroviral treatment (ART)

Forty samples collected from HIV-1 AIDS and asymptomatic patients in 2002 and 2003 before the initiation of antiretroviral treatment (ART), most in poorly investigated regions of Ghana were retrospectively examined. For baseline data on genetic diversity before therapy, env, gagand pol phylogenetic analysis was generated. pol was further analysed for potential resistance to...

Author(s): James A. M. Brandful, Daniel Candotti and Jean-Pierre Allain

July 2012

Various neurological manifestations in HIV positive patients, their outcome and its correlation with CD4 counts- A tertiary centre experience in North Indian population

The central nervous system (CNS) is among the most frequent and main target of HIV infection in severely immunocompromised patients. Neurological manifestations occur due to either primary pathologic process of HIV or secondary to opportunistic infection. The present study was conducted to ascertain the prevalence of various neurological manifestations in HIV positive patients, correlation of CD4 levels in CNS...

Author(s): M. L. Patel, Rekha Sachan, V. Atam, S. C. Chaudhary and Abhinav Gupta