African Journal of
Bacteriology Research

  • Abbreviation: J. Bacteriol. Res.
  • Language: English
  • ISSN: 2006-9871
  • DOI: 10.5897/JBR
  • Start Year: 2009
  • Published Articles: 112

Full Length Research Paper

Antimicrobial susceptibility of Pseudomonas aeruginosa strains in Bamako, Mali

Dicko O. A.
  • Dicko O. A.
  • Laboratoire de Biologie Médicale et Hygiène Hospitalière du CHU du Point-G, Bamako, Mali.
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Traoré A.
  • Traoré A.
  • Laboratoire de Biologie Médicale et Hygiène Hospitalière du CHU du Point-G, Bamako, Mali.
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Maiga A.
  • Maiga A.
  • Laboratoire de Biologie Médicale et Hygiène Hospitalière du CHU du Point-G, Bamako, Mali.
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Coulibaly D. M.
  • Coulibaly D. M.
  • Laboratoire de Biologie Médicale et Hygiène Hospitalière du CHU du Point-G, Bamako, Mali.
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Diarra B.
  • Diarra B.
  • Faculté de Médecine et d’Odontostomatologie de Bamako (FMOS), USTTB, Bamako, Mali.
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Maiga I. I.
  • Maiga I. I.
  • Laboratoire de Biologie Médicale et Hygiène Hospitalière du CHU du Point-G, Bamako, Mali.
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  •  Received: 25 January 2021
  •  Accepted: 03 September 2021
  •  Published: 30 September 2021

Abstract

Pseudomonas aeruginosa is generally susceptible to antibiotics of the families of Beta-lactam, aminoglycosides and quinolones. The aim of this study was to evaluate the antimicrobial susceptibility of P. aeruginosa strains in Bamako, Mali. P. aeruginosa strains were isolated on Drigalski agar. Antimicrobial susceptibility testing was performed using the disc diffusion method on Mueller-Hinton agar. Among 317 non repetitive strains recovered from 2010 to 2019, there were 246 (77.6%) hospital strains and 71 (22.4%) extra-hospital strains. Colistin (100%), imipenem (98.4%), ceftazidime (89.3%), amikacin (85.2%) and piperacillin (72.3%) were the most active antibiotics against our P. aeruginosa strains. Of the strains 11 (3.5%) were multi-drug resistant (MDR) and 5 (1.6%) were extensively drug-resistant (XDR). The extra-hospital P. aeruginosa strains were more susceptible to aztreonam (91.5% vs 60.6%; P = 0.0000018), piperacillin (84.5% vs 68.7%; P = 0.013), gentamycin (84.5% vs 62.2%; P = 0.00071), netilmicin (56% vs 32.5%; P = 0.0045) and ciprofloxacin (79% vs 65.4%; P = 0.0455) than the hospital strains.  Colistin, imipenem, ceftazidim, amikacin and piperacillin have a high-level activity against P. aeruginosa in Bamako.

 

Key words: Pseudomonas aeruginosa, antimicrobial susceptibility, Bamako, Mali.