Journal of
General and Molecular Virology

  • Abbreviation: J. Gen. Mol. Virol.
  • Language: English
  • ISSN: 2141-6648
  • DOI: 10.5897/JGMV
  • Start Year: 2009
  • Published Articles: 37

Full Length Research Paper

Prevalence of Hepatitis B surface antigen and Hepatitis C virus antibodies among pre-surgery screened patients in Khartoum, Central Sudan

  Emad-Aldin Ibrahim Osman1,2*, Nagwa Ahmed Abdulrahman2, Osman Abbass2, Waleed Hussein Omer3, Hafi Anwer Saad4 and Muzamil Mahdi Abdel Hamid5
  1Department of Haematology, Faculty of Medical Laboratory Sciences, Elrazi College of Medical and Technological Sciences, Khartoum, Sudan. 2Department of Clinical Laboratories, Al-Shaab Teaching Hospital, Federal  Ministry of Health, Khartoum, Sudan. 3Al-Neelain Medical Research Center, Faculty of Medicine and Health sciences, Al-Neelain University, Khartoum, Sudan. 4Department of Community Medicine, Faculty of Medicine, University of Shendi, Shendi, Sudan. 5Department of Molecular Biology, Institute of Endemic Diseases, University of Khartoum, P. O. Box 102, Khartoum, Sudan
Email: [email protected]

  •  Accepted: 29 February 2012
  •  Published: 31 October 2012

Abstract

 

The prevalence of Hepatitis B and C infection varies between different regions of Sudan according to several published reports. The present study is a descriptive hospital-based study aimed to estimate prevalence of Hepatitis B surface antigen and anti-Hepatitis C virus antibodies among 3172 patients undergoing surgery at Al-Shaab Teaching Hospital in Khartoum from April 2008 to April 2011. All patients were screened by rapid chromatography immunoassay for qualitative detection of Hepatitis B surface antigen and anti-Hepatitis C virus antibodies. The mean age of the studied subjects was 44 years; 61.1% of them were males and 38.9% were females. Hepatitis B surface antigen was detected in 156 patients (4.91%), while anti-Hepatitis C virus antibodies were detected in 58 patients (1.82%). The prevalence of Hepatitis B surface antigen is slightly higher in males (5.46%), than females (4.04%); however, it is statistically insignificant (P= 0.08). In conclusion, the present study reported a prevalence of Hepatitis B surface antigen which is lower than what has previously been reported in Sudan.

 

Key words: Hepatitis B virus (HBV), hepatitis C virus (HCV), prevalence, Khartoum, Sudan