Journal of
Infectious Diseases and Immunity

  • Abbreviation: J. Infect. Dis. Immun.
  • Language: English
  • ISSN: 2141-2375
  • DOI: 10.5897/JIDI
  • Start Year: 2009
  • Published Articles: 94

Case Report

Aspergillus tracheobronchitis in an immunocompetent critically ill patient

Steve Reynolds1*, Stephen Blackie2 and Jason Faulds3,4
1Department of Surgery, University of British Columbia, Room 3100, 910 West 10th Avenue, Vancouver, B.C., V5Z 4E3, Canada. 2Department of Internal Medicine, Royal Columbian Hospital, New Westminster, BC Canada. 3Division of Infectious Diseases and Critical Care, UBC Department of Medicine, Royal Columbian Hospital, New Westminster, BC, Canada.
Email: [email protected]

  •  Accepted: 25 March 2011
  •  Published: 30 April 2011

Abstract

Aspergillus tracheobronchitis (ATB) is a rare cause of respiratory failure in the critical care unit. Most commonly occurring in immunocompromised patients with underlying haematological malignancy, solid organ transplant, or HIV/AIDs, ATB is infrequently encountered in patients without underlying immunologic derangement.  This brief report describes a single case of ATB in a critically ill patient with no known history of immunosuppression. Bronchoscopy confirmed the diagnosis of ATB and Aspergillus fumigatus was cultured from bronchoscopy and autopsy specimens. The diagnostic features of A. tracheobronchitis are highlighted with bronchoscopic and post-mortem images. A literature review highlights the diagnostic and therapeutic challenges associated with A. tracheobronchitis in the critically ill.

 

Key words: Aspergillus tracheobronchitis, respiratory failure, fungal infections.