Full Length Research Paper
Abstract
Ginkgo leaf extract were studied for their protective effects against liver injury induced using carbon tetrachloride (CCl4) in mice. Mice were administered CCl4 by intraperitoneal injection and received a normal diet or normal diet with various Ginkgo leaf extract. Ginkgo leaf extract significantly reduced the liver damage and improving immunity activities by increasing liver index, B lymphocyte transfer index, Natural killer cell activity and phagocytic activity and decreasing liver IL-1β and TNF-α levels in a dose dependent manner. These results suggested that Ginkgo leaf extract may protect the liver against CCl4-induced injury by enhancing immunity activity.
Key words: Ginkgo leaf extract, mice, IL-1β, natural killer cell activity, B lymphocyte transfer index, immunity.
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