Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Antimicrobial evaluation of endophytic fungi extracts isolated from Casearia sylvestris

Ernane Gerre Pereira Bastos
  • Ernane Gerre Pereira Bastos
  • Laboratório de Microbiologia Ambiental e Biotecnologia (LAMBIO), Palmas-TO, Brazil.
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Aline Aires Aguiar
  • Aline Aires Aguiar
  • Laboratório Microbiologia Geral e Aplicada, Universidade Federal do Tocantins, 77001-923 Palmas-TO, Brazil.
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Adriana Idalina Torcato de Oliveira
  • Adriana Idalina Torcato de Oliveira
  • Laboratório Microbiologia Geral e Aplicada, Universidade Federal do Tocantins, 77001-923 Palmas-TO, Brazil.
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Juliana Fonseca Moreira da Silva
  • Juliana Fonseca Moreira da Silva
  • Laboratório Microbiologia Geral e Aplicada, Universidade Federal do Tocantins, 77001-923 Palmas-TO, Brazil.
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Raphael Sanzio Pimenta
  • Raphael Sanzio Pimenta
  • Laboratório de Microbiologia Ambiental e Biotecnologia (LAMBIO), Palmas-TO, Brazil.
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  •  Received: 29 September 2017
  •  Accepted: 25 October 2017
  •  Published: 17 November 2017

Abstract

Due to widespread bacterial resistance to commercial antibiotics, the search for capable substances to combating these microorganisms became a priority. In this context, the endophytic fungi gained prominence as potential producers of bioactive substances with pharmacological interest. It is considering that endophytes are still poorly studied, especially in tropical species. The antibacterial and antifungal potential of endophytic fungi associated with the medicinal plant Casearia sylvestris were isolated and evaluated. A total of 162 strains were obtained, among these strains, 34 were selected for antimicrobial assays, after molecular sorting with oligonucleotide (GTG)5. A total of 25 isolates showed some antifungal and / or antibacterial activity against the bacteria Staphylococcus aureus, Listeria monocytogenes, Pseudomonas aeruginosa, Escherichia coli, and yeasts Candida albicans and Candida tropicallis. The results show the endophytic fungi present in C. sylvestris have a high potential to produce bioactive compounds inhibiting pathogenic microorganisms.

 

Key words: Endophytic fungi, Casearia sylvestris, antimicrobial, secondary metabolites.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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