Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Areca nut oil with arecoline can enhance hypolipidemia in rats

Zhou Wen-hua1,2*, Jiang Ai-min1, P. U. Yi-xin2, Zhang Hai-de3 and Ren Honghao2
1College of Food Science, South China Agricultural University, Guangzhou 510642, China. 2College of Food Science and Engineering, Central South University of Forestry and Technology, Changsha 410004, China. 3Food Science College of Hainan University, Danzhou, Hainan 410004, China.
Email: [email protected]

  •  Accepted: 25 August 2010
  •  Published: 04 June 2011

Abstract

Both Areca nut oil (OL) and arecoline play some roles in moderating hypolipidemia but the pathways may be different. The authors hypothesize OL plus arecoline can lead to an improved hypolipidemia in animal model. In this study, the fed rats with series doses of OL alone or OL plus arecoline. The gaining weight, the level of total cholesterol (TC), triacylglyceride (TG), high density lipoprotein cholesterol (HDL-C) and arteriosclerosis index (AI) from the rats were then examined. The authors found low dose of OL (0.335 g·kg-1) plus arecoline (3 mg·kg-1) could significantly reduce the level of TC and AI, and increase the level of HDL-C compared to other groups. They conclude OL (0.335 g·kg-1) plus arecoline (3 mg·kg-1) can play a synergistic role in enhancing hypolipidemia in rats.

 

Key words: Areca nut oil, total cholesterol, triglyceride, high density lipoprotein cholesterol, arteriosclerosis index.

Abbreviation

OL, areca nut oil; OB, OL plus arecoline; TC, total cholesterol; TG,triacylglyceride; HDL-C, high density lipoprotein cholesterol; AI, arteriosclerosis index.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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