Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Fast identification of flavonoids in the roots of Sophora flavescens by on-flow LC-NMR

Su Jin Kim1,2, Sang Min Kim1, Min Cheol Kim3, Suk Woo Kang1 and Byung Hun Um1*
1Korea Institute of Science and Technology (KIST) Gangneung Institute, Gangneung 210-340, Republic of Korea. 2Division of Chemistry, College of Natural Sciences, Gangneung-Wonju National University, Gangneung 210-702, Republic of Korea. 3Graduate School of East-West Medical Science, Kyung Hee University, Youngin 446-701, Republic of Korea.
Email: [email protected]

  •  Accepted: 22 June 2010
  •  Published: 04 December 2010

Abstract

Sophora flavescens Ait (Leguminosae) is a Chinese herbal medicine. Sophorae radix, the dried roots of S. flavescens, has been used for various diseases including atherosclerosis and arrhythmias. For the direct identification of the compounds present in Sophorae radix, the hyphenated LC-NMR technique has been applied. WET solvent suppression and scout scan techniques were used to suppress solvent peaks in on-flow LC-NMR experiment. Six prenylflavonoids were identified successfully as kushenol U (1), kurarinone (2), sophoraflavanone G (3), leachianone A (4), kuraridin (5) and kushenol A (6).

 

Key words: LC-hyphenated, on-flow LC-NMR, prenyl-flavonoid, Sophora flavescens.

Copyright © 2024 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

Back to Vol. 4 No. 23
Back to articles
  • Articles on Google by:
SUBSCRIBE TO RSS
SUBMIT MANUSCRIPT
CONFERENCES