Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3834

Full Length Research Paper

Evaluation of in vitro antioxidant and antitumour activities of Astragalus membranaceus aqueous extract

Xian-zhong Peng*, Shao-shui Chen, Fang-ling Ning, Mian-li Li
Department of Oncology, Affiliated Hospital of Binzhou Medical College, Binzhou 256603, China
Email: [email protected]

  •  Accepted: 22 September 2011
  •  Published: 09 December 2011

Abstract

Aqueous extracts of Astragalus membranaceus (AMEE) were prepared in this study. In vitroantioxidant and antitumour activities of aqueous extracts of A. membranaceus were evaluated. The aqueous extracts exhibited could effectively scavenge superoxide anion, Hydrogen peroxide, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals and reduce 2,2'-azobis(2-amidinopropane) hydrochloride (AAPH)-induced human erythrocytes hemolysis. Moreover, aqueous extracts of A. membranaceus could still effectively dose-dependently inhibit against the human Gastric cancer cell line SGC-7901 and human hepatoma SMMC-7721 cells growth at the given dose range. The results indicate that the aqueous extracts of A. membranaceus have a very potent antioxidant and antitumour activity.

 

Key words: Astragalus membranaceus aqueous extracts, antioxidant, antitumour, SGC-7901, SMMC-7721.

Copyright © 2024 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

Back to Vol. 5 No. 29
Back to articles
  • Articles on Google by:
SUBSCRIBE TO RSS
SUBMIT MANUSCRIPT
CONFERENCES