Abstract

In order to explore the mechanism of berberine hydrochloride in treating diabetes, antioxidant activities of the berberine hydrochloride in vitro were carried out. In the present study, our study aimed to examine the antioxidant activity of berberine hydrochloride using different assays including: reducing power, 2,2-diphenyl 1-picrylhydrazyl (DPPH) radical scavenging assay, ABTS radical scavenging assay, superoxide anion and hydroxyl radical scavenging activity. The results exhibited that berberine hydrochloride has significant reductive ability and radicals scavenging effects, especially on ABTS, hydroxyl radicals and DPPH radicals.

Key words: Berberine hydrochloride, antioxidant activity, free radicals, in vitro.