Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Antimicrobial and antioxidant activities of medicinal plant species Ornithogalum alpigenum stapf. from Turkey

A. Afacan Makasci1, R. Mammadov2*, O. Dusen2 and H. I. Isik3
1Department of Chemistry, Faculty of Science and Arts, N. Kemal University, Tekirdag, Turkey. 2Department of Biology, Faculty of Science and Arts, Pamukkale University, 20017 Denizli, Turkey. 3Department of Biology, Faculty of Science and Arts, Mugla University, 48000 Mugla, Turkey.
Email: [email protected]

  •  Accepted: 31 March 2010
  •  Published: 18 August 2010

Abstract

In this study, examination of the antioxidant and antimicrobial properties inherent in leaves and bulbs of geophytic, endemic species, Ornithogalum alpigenum Stapf. were carried out. Of all the extracts derived from the leaves and bulbs of this plant with various solvents, the acetone bulb extract was most inhibitory to the growth of with inhibition zone diameter of 12 ± 2 mm Candida albicans ATCC 10239. It was determined that the extracts of Ornithogalum Leaf-ethanol (OLE) (11 ± 2 mm diameter) and OTA (8 ± 2 mm diameter) were effective on Bacillus subtilis ATCC 6633, OTB (9 ± 1 mm diameter) and OTA (10 ± 2 mm diameter) was effective onBacillus cereus RSKK 86. We studied that the total antioxidant and free radical scavenging activities of the extractions obtained from O. alpigenum Stapf. Total antioxidant activity of the extract from O. alpigenum Stapf. was determined usingb–carotene-linoleic acid model system and was found the highest antioxidant activity of 88.12 ± 0.9% in methanol bulb extracts. Free radical scavenging activity of the extracts using the free radical 1,1-diphenyl-2-picrylhydrazyl (DPPH) was also determined. The overall results showed that some solutions have values (90.9% > 90.5% > 90.4% > 88.4%) very close to those of Butylated Hydroxytoluene (BHT) (90.0%). The leaf extracts were more potent with respect to free radical scavenging activity.

 

Key words: Ornithogalum alpigenum, antimicrobial activity, antioxidant activity,Butylated Hydroxytoluene, 1,1-diphenyl-2-picrylhydrazyl, geophytes, organic extracts, radical scavenging.