Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Composition and antioxidant activity in vitro of different St. John’s Wort (Hypericum perforatum L.) extracts

Gian Gabriele Franchi*, Cristina Nencini, Elga Collavoli and Paola Massarelli
Department of Neurology, Neurosurgery and Behavioral Sciences, Section of Pharmacology “Giorgio Segre”, University of Siena, Strada delle Scotte 6, I 53100 Siena, Italy.
Email: [email protected]

  •  Accepted: 04 July 2011
  •  Published: 09 September 2011

Abstract

Current literature reports a wide variability in active compounds content in marketedHypericum (Hypericum perforatum L.) preparations. In order to avoid influences by soil, climate, collection time and storage, several extracts were prepared, with different solvents, from a single stock of plant drug, collected from the wild. They were high performance liquid chromatography (HPLC) analyzed, and results were coupled with an evaluation of the antioxidant activity in vitro of each extract. Also water extracts maintained a good activity, although they were obviously lacking hypericin and hyperforin. In this sense, the home made St. John’s wort teas should be re-valued as possible beverages with interesting antioxidant properties.

 

Key words: Antioxidant activity, flavonoids, hyperforinhypericin, Hypericum perforatum L., St. John’s wort tea.