Abstract

The in vitro antimicrobial and phytochemical activities of the crude ethanolic leaf extract of Acacia nilotica on Campylobacter coli isolated from goats in Gwagwalada Abattoir was investigated. Hydrolysable tannins, saponin, saponin glycosides, volatile oils, phenols, triterpenes, flavonoids and alkaloid were present in the extract. Minimum inhibitory concentration was 70 mg/ml of the extract related to standardized bacteria colony of 3 x 10⁸ organisms per ml. The highest zone of inhibition was observed with the 70 mg/ml concentration, following isolation and inoculation of test organisms on Muller Hinton Agar incubated at 37^oC for 24 h. The basis of this plant extract in the traditional treatment of diarrhea in human is highlighted.

Key words: Acacia nilotica, antimicrobial activity, chemical constituents,Campylobacter coli.