Abstract

The present investigations evaluate the inhibitory efficacy of different solvent extracts prepared from seven ethno-medicinal plant species against four human pathogenic bacteria. Antibacterial activity, tested by agar well diffusion method revealed that, Boerhaavia diffusaand Andrographis paniculata showed maximum inhibitory activity on pathogenic bacteria comparable with streptocycline efficacy. The most susceptible pathogen in the present investigation was found to be Klebsiella pneumoneae followed by Staphylococcus aureuswhile Pseudomonas fluorescence was the most resistant. Afterwards, in qualitative phytochemical analysis alkaloids, tannins and flavonoids were commonly found as majority from tested plant species. Further, thin layer chromatography detected recurrently occurring flavonoidal compounds, namely, Apigenin and Chrysoeriol in different plant species.

Key words: Ethno-medicinal plants, human pathogen, bacteria, phytochemical, thin layer chromatography.