Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Chemical profile, antimicrobial activity, toxicity on Artemia salina and anti-acetylcholinesterase enzyme essential oil from Bauhinia ungulata L. (Fabaceae) leaves

Sandra R. N. A. Medeiros
  • Sandra R. N. A. Medeiros
  • Post-Graduate in Chemistry Program, Center for Research and Post-Graduate Studies in Science and Technology, NPPGCT, UFRR, Av Capitão Ene Garcez, n. 2413, Campus Paricarana, CEP 69310-000, Boa Vista-RR-Brazil.
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Antonio A. de Melo Filho
  • Antonio A. de Melo Filho
  • Post-Graduate in Chemistry Program, Center for Research and Post-Graduate Studies in Science and Technology, NPPGCT, UFRR, Av Capitão Ene Garcez, n. 2413, Campus Paricarana, CEP 69310-000, Boa Vista-RR-Brazil.
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Habdel N. R. da Costa
  • Habdel N. R. da Costa
  • Post-Graduate in Biodiversity and Biotechnology Program, Bionorte, State Coordination of Roraima, Federal University of Roraima - UFRR, Campus Cauamé, BR 174, Km 12, District Monte Cristo, CEP 69310-250, Boa Vista-RR-Brazil.
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Francisco dos Santos Silva
  • Francisco dos Santos Silva
  • Post-Graduate in Biodiversity and Biotechnology Program, Bionorte, State Coordination of Roraima, Federal University of Roraima - UFRR, Campus Cauamé, BR 174, Km 12, District Monte Cristo, CEP 69310-250, Boa Vista-RR-Brazil.
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Ricardo C. dos Santos
  • Ricardo C. dos Santos
  • Post-Graduate in Biodiversity and Biotechnology Program, Bionorte, State Coordination of Roraima, Federal University of Roraima - UFRR, Campus Cauamé, BR 174, Km 12, District Monte Cristo, CEP 69310-250, Boa Vista-RR-Brazil.
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Jacqueline A.Takahashi
  • Jacqueline A.Takahashi
  • Department of Chemistry, Institute of Exact Sciences, Federal University of Minas Gerais, UFMG, Av Antonio Carlos, n. 6627, Pampulha, CEP 31270-901, Belo Horizonte-MG-Brazil.
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Vany P. Ferraz
  • Vany P. Ferraz
  • Department of Chemistry, Chromatography Laboratory, Institute of Exact Sciences, UFMG, Belo Horizonte-MG-Brazil.
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Ana C. G. R. de Melo
  • Ana C. G. R. de Melo
  • Post-Graduate in Biodiversity and Biotechnology Program, Bionorte, State Coordination of Roraima, Federal University of Roraima - UFRR, Campus Cauamé, BR 174, Km 12, District Monte Cristo, CEP 69310-250, Boa Vista-RR-Brazil.
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Pedro R. E. Ribeiro
  • Pedro R. E. Ribeiro
  • Post-Graduate in Biodiversity and Biotechnology Program, Bionorte, State Coordination of Roraima, Federal University of Roraima - UFRR, Campus Cauamé, BR 174, Km 12, District Monte Cristo, CEP 69310-250, Boa Vista-RR-Brazil.
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Andreina G. de Andrade Laranjeira
  • Andreina G. de Andrade Laranjeira
  • Post-Graduate in Biodiversity and Biotechnology Program, Bionorte, State Coordination of Roraima, Federal University of Roraima - UFRR, Campus Cauamé, BR 174, Km 12, District Monte Cristo, CEP 69310-250, Boa Vista-RR-Brazil.
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Angela K. Kamezaki
  • Angela K. Kamezaki
  • Post-Graduate in Biodiversity and Biotechnology Program, Bionorte, State Coordination of Roraima, Federal University of Roraima - UFRR, Campus Cauamé, BR 174, Km 12, District Monte Cristo, CEP 69310-250, Boa Vista-RR-Brazil.
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Regildo M. G. Martins
  • Regildo M. G. Martins
  • Post-Graduate in Biodiversity and Biotechnology Program, Bionorte, State Coordination of Roraima, Federal University of Roraima - UFRR, Campus Cauamé, BR 174, Km 12, District Monte Cristo, CEP 69310-250, Boa Vista-RR-Brazil.
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Flavio da Silva Paulino
  • Flavio da Silva Paulino
  • Post-Graduate in Biodiversity and Biotechnology Program, Bionorte, State Coordination of Roraima, Federal University of Roraima - UFRR, Campus Cauamé, BR 174, Km 12, District Monte Cristo, CEP 69310-250, Boa Vista-RR-Brazil.
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  •  Received: 08 April 2016
  •  Accepted: 28 June 2016
  •  Published: 03 August 2016

Abstract

Bauhinia ungulata L. species, belongs to the genus Bauhinia, popularly known as pata de vaca, is among the species of medicinal employ in Brazil, used to treat diabetes. The aim of this study was to characterize the chemical composition, antimicrobial activity, toxicity on Artemia salina and acetylcholinesterase enzyme inhibition by essential oil from B. ungulata L. The chromatographic analysis revealed 18 components, the majority were the β-caryophyllene (15.9%), caryophyllene oxide (9.2%), α-humulene (8.1%), epi-γ-eudesmol (7.5%), α-bisabolol (4.7%), copaene (3.5%), nerolidol (3.3%), α-bisabolol oxide B (2.5%), spathulenol (2.1%). The essential oil showed high toxicity compared to the tests with Artemia salina and inhibited 95.96%±0.62 of the acetylcholinesterase enzyme. The microorganisms show antimicrobial inhibition with Candida albicans (85%), Bacillus cereus (65.5%) and Staphylococcus aureus (66.4%), Salmonella typhimurium (68.7%) and Citrobacter freundii (46.1%). The oil showed great potential when tested in bioassays.

Key words: Volatile oil, cytotoxicity on microcrustacean, antifungal, antibacterial, neurodegenerative disease.

Copyright © 2024 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

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