Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3834

Full Length Research Paper

Diversity of plants used in the treatment of Helicobacter pylori associated morbidities in the Nkonkobe municipality of the Eastern Cape province of South Africa

Njume C.1, Afolayan A. J.1 and Ndip R. N.1,2*
1School of Biological and Environmental Sciences, Faculty of Science and Agriculture, University of Fort Hare, P/Bag X1314, Alice 5700, South Africa. 2Department of Biochemistry and Microbiology, Faculty of Science, University of Buea, Box 63, Buea, Cameroon.
Email: [email protected] or [email protected]

  •  Accepted: 11 April 2011
  •  Published: 18 July 2011

Abstract

Helicobacter pylori is a major cause of gastro-duodenal pathologies. Expenses associated with combination therapy and the adverse effects of the treatment regimens have led to increased usage of ethnomedicines in the management of infections. Despite the usage of plants in the management of infections in the Nkonkobe municipality, empirical studies to document the specific plant species used by traditional doctors are lacking. This study was conducted to document the various plant families and species used in the management ofHpylori associated morbidities in the Nkonkobe municipality. A semi-structured questionnaire was used to interview the local dwellers including traditional doctors, herbalists and hawkers in traditional medicine. The plant parts used, preparation, mode of administration and dosages were recorded. Seventeen plant species belonging to 13 genera and 11 families were collected and identified by their vernacular and scientific names. The Asphodelaceae was the most represented family (4 species), followed by Apocynaceae (3 species) and Loganiaceae (2 species). The plant parts most frequently used were the roots (35.3%), followed by the leaves and stem barks (23.5% each). Further research is needed to scientifically correlate treatment claims with folkloric uses and to isolate the plants active components, determine their in-vivo potencies and toxicity.

 

Key words: Helicobacter pylori, stomach morbidities, ethnomedicines, Nkonkobe municipality, South Africa.