Phytochemicals are non-nutritive chemical compounds that occur naturally in plants and have diverse properties. Based on the traditional or folklore knowledge in this present study two medicinal plants, Purpurascens posumbes, and Polygonum posumbes were analyzed for phytochemicals and their antimicrobial activities. Qualitative analysis of Purpurascens posumbes showed alkaloids, phenol, flavonoids, tannins, coumarins, and terpenoids. On the other Polygonum posumbes showed the presence of alkaloids, phenol, Flavonoids, tannins, carbohydrates, coumarins. The anti-microbial activities of both plants were tested against Staphylococcus aureus and Klebsiella pneumoniae. Purpurascens posumbes at 1 mg/ml depicted diameter of inhibition zone (ZOI) are 6.96±0.25 mm, and 7.7±0.2 mm respectively. Whereas Polygonum posumbes described ZOI are 6.1±0.1 mm, and 8.06±0.20 mm, respectively. In addition, Purpurascens posumbes displayed a total antioxidant capacity of 105.09 ± 3.47 and Polygonum posumbes 98.03 ± 2.32 (mg/g ascorbic acid equivalent). Both plants displayed considerable antioxidant activity which is justified by the presence of polyphenol-like phenol and flavonoids. This study provides comprehensive knowledge and potential guidance in exploring the medicinal values of active compounds and conserving traditional medicinal practices.

Keywords: Purpurascens posumbes, Polygonum posumbes, phytochemical, anti-oxidant, anti-microbial, Qualitative analysis.