Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Revisiting the linkage between ethnomedical use and development of new medicines: A novel plant collection strategy towards the discovery of anticancer agents

Joshua M. Henkin
  • Joshua M. Henkin
  • Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, 833 S. Wood St., Chicago, Illinois 60612, USA.
  • Google Scholar
Kongmany Sydara
  • Kongmany Sydara
  • Institute of Traditional Medicine, Ministry of Health, Vientiane Capital, Lao People's Democratic Republic.
  • Google Scholar
Mouachanh Xayvue
  • Mouachanh Xayvue
  • Institute of Traditional Medicine, Ministry of Health, Vientiane Capital, Lao People's Democratic Republic.
  • Google Scholar
Onevilay Souliya
  • Onevilay Souliya
  • Institute of Traditional Medicine, Ministry of Health, Vientiane Capital, Lao People's Democratic Republic.
  • Google Scholar
A. Douglas Kinghorn
  • A. Douglas Kinghorn
  • Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Ohio State University, 500 W. 12th Ave., Columbus, OH 43210, USA.
  • Google Scholar
Joanna E. Burdette
  • Joanna E. Burdette
  • Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, 833 S. Wood St., Chicago, Illinois 60612, USA.
  • Google Scholar
Wei-Lun Chen
  • Wei-Lun Chen
  • Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, 833 S. Wood St., Chicago, Illinois 60612, USA.
  • Google Scholar
Bethany G. Elkington
  • Bethany G. Elkington
  • Science and Education, Field Museum, 1400 S. Lake Shore Drive, Chicago, Illinois 60605, USA.
  • Google Scholar
Djaja D. Soejarto
  • Djaja D. Soejarto
  • Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, 833 S. Wood St., Chicago, Illinois 60612, USA.
  • Google Scholar


  •  Received: 31 August 2017
  •  Accepted: 03 October 2017
  •  Published: 25 October 2017

References

Balée WL, Erickson CL (2006). Time and complexity in historical ecology: studies in the neotropical lowlands. Columbia University Press.
Crossref

 

Balunas MJ, Jones WP, Chin YW, Mi Q, Farnsworth NR, Soejarto DD, Cordell GA, Swanson SM, Pezzuto JM, Chai HB, Kinghorn AD (2006). Relationships between inhibitory activity against a cancer cell line panel, profiles of plants collected, and compound classes isolated in an anticancer drug discovery project. Chem. Biodivers. 3(8):897-915.
Crossref

 
 

Bletter N (2007). A quantitative synthesis of the medicinal ethnobotany of the Malinké of Mali and the Asháninka of Peru, with a new theoretical framework. J. Ethnobiol. Ethnomed. 3(1):36.
Crossref

 
 

Campbell DG (2007). A land of ghosts: the braided lives of people and the forest in far western Amazonia. Rutgers University Press. Available at: 

View

 
 

Coats SJ, Garnier-Amblard EC, Amblard F, Ehteshami M, Amiralaei S, Zhang H, Zhou L, Boucle SR, Lu X, Bondada L, Shelton JR, Li H, Liu P, Li C, Cho JH, Chavre SN, Zhou S, Mathew J, Schinazi RF (2014). Chutes and ladders in hepatitis C nucleoside drug development. Antiviral Res. 102:119-147.
Crossref

 
 

Elkington BG, Southavong B, Sydara K, Souliya O, Vanthanouvong M, Nettavong K, Thammachack B, Pak DH, Riley MC, Franzblau SG, Soejarto DD (2009). Biological evaluation of plants of Laos used in the treatment of tuberculosis in Lao traditional medicine. Pharm. Biol. 47(1):26-33.
Crossref

 
 

Elkington BG, Sydara K, Newsome A, Hwang CH, Lankin DC, Simmler C, Napolitano JG, Ree R, Graham JG, Gyllenhaal C, Bouamanivong S, Souliya O, Pauli GF, Franzblau SG, Soejarto DD (2014). New finding of an anti-TB compound in the genus Marsypopetalum (Annonaceae) from a traditional herbal remedy of Laos. J. Ethnopharmacol. 151:903-911.
Crossref

 
 

Fadeyi SA, Fadeyi OO, Adejumo AA, Okoro C, Myles EL. (2013). In vitro anticancer screening of 24 locally used Nigerian medicinal plants. BMC Complement. Altern. Med. 13(1):79.
Crossref

 
 

Getasetegn M, Tefera Y (2016). Biological Activities and Valuable Compounds from Five Medicinal Plants. Nat. Prod. Chem. Res. 4:220.
Crossref

 
 

Gyllenhaal C, Kadushin MR, Southavong B, Sydara K, Bouamanivong S, Xaiveu M, Xuan LT, Hiep NT, Hung NV, Loc PK, Dac LX (2012). Ethnobotanical approach versus random approach in the search for new bioactive compounds: support of a hypothesis. Pharm. Biol. 50(1):30-41.
Crossref

 
 

He Z-D, Ma C-Y, Sydara K, Bouamanivong S, Zhang H-J, Tan GT, Tames P, Southavong B, Soejarto DD, Pezzuto JM, Fong HHS (2005). Antimalarial Constituents from Nauclea orientalis (L.) L. Chem. Biodivers. 2(10):1378-1386.
Crossref

 
 

He ZD, Ma CY, Tan GT, Sydara K, Tamez P, Southavong B, Bouamanivong S, Soejarto DD, Pezzuto JM, Fong HHS, Zhang HJ (2006). Rourinoside and rouremin, antimalarial constituents from Rourea minor. Phytochemistry 67:1378-1384.
Crossref

 
 

Kinghorn AD, Farnsworth NR, Soejarto DD, Cordell GA, Swanson SM, Pezzuto JM, Wani MC, Wall ME, Oberlies NH, Kroll DJ, Kramer RA, Rose WC, Vite GD, Fairchild CR, Peterson RW, Wild R (2003). Novel strategies for the discovery of plant-derived anticancer agents. Pharm. Biol. 41(Supplement):53-67.
Crossref

 
 

Kinghorn AD, Carcache de Blanco EJ, Chai HB, Orjala J, Farnsworth NR, Soejarto DD, Oberlies NH, Wani MC, Kroll DJ, Pearce CJ, Swanson SM, Kramer RA, Rose WC, Fairchild CR, Vite GD, Emanuel S, Jarjoura D, Cope FO (2009). Discovery of anticancer agents of diverse natural origin. Pure Appl. Chem. 81(6):1051-1063.
Crossref

 
 

Kinghorn AD, DE Blanco EJ, Lucas DM, Rakotondraibe HL, Orjala J, Soejarto DD, Oberlies NH, Pearce CJ, Wani MC, Stockwell BR, Burdette JE, Swanson SM, Fuchs JR, Phelps MA, Xu L, Zhang X, Shen YY (2016). Discovery of anticancer agents of diverse natural origin. Anticancer Res. 36(11):5623-5637.
Crossref

 
 

Kumar V, Abbas AK, Fausto N, Aster JR (2010). Cotran pathologic basis of disease. 2010. Saunders Elsevier, 8th ed. P 784.

 
 

Leonti M, Weckerle CS (2015). Quantitative and comparative methods in ethnopharmacology. In: Ethnopharmacology, Heinrich M, Jäger AK (Eds.), Wiley Blackwell. pp. 41-51.
Crossref

 
 

Libman A, Zhang HJ, Ma CY, Southavong B, Sydara K, Bouamanivong S, Tan GT, Fong HHS, Soejarto DD (2008). An antimalarial steroidal glycoside from Gongronema napalense. Asian J. Tradit. Med. 3:203-210.

 
 

Ma CY, Musoke SF, Tan GT, Sydara K, Bouamanivong S, Southavong B, Soejarto DD, Fong HHS, Zhang HJ (2008). Study of antimalarial activity of chemical constitutents from Diospyros quaesita. Chem. Biodivers. 5:2442-2448.
Crossref

 
 

Mazzio EA, Soliman KF (2009). In vitro screening for the tumoricidal properties of international medicinal herbs. Phytother. Res. 23(3):385-398.
Crossref

 
 

Odonne G, Houël E, Bourdy G, Stien D (2017). Treating leishmaniasis in Amazonia: A review of ethnomedicinal concepts and pharmaco-chemical analysis of traditional treatments to inspire modern phytotherapies. J. Ethnopharmacol. 199:211-230.
Crossref

 
 

Ott J (1998). The Delphic bee: Bees and toxic honeys as pointers to psychoactive and other medicinal plants. Econ. Bot. 52(3):260-266.
Crossref

 
 

Paull KD, Shoemaker RH, Hodes L, Monks A, Scudiero DA, Rubinstein L, Plowman J, Boyd MR (1989). Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and compare algorithm. J. Natl. Cancer Inst. 81(14):1088-1092.
Crossref

 
 

Pan SY, Zhou SF, Gao SH, Yu ZL, Zhang SF, Tang MK, Sun JN, Ma DL, Han YF, Fong WF, Ko KM (2013). New perspectives on how to discover drugs from herbal medicines: CAM's outstanding contribution to modern therapeutics. Evid.-Based Complement. Altern. 2013: 23634172.
Crossref

 
 

Peruchot M, Forrester K, Almoguera C, Hant K, Grizzle WE (1987). Detection of high incidence of K-ras oncogenes during human colon tumorigenesis. Nature 327:298-303.
Crossref

 
 

Ren Y, Benatrehina PA, Acu-a UM, Yuan C, Chai HB, Ninh TN, de Blanco EJ, Soejarto DD, Kinghorn AD (2014). Isolation of bioactive rotenoids and isoflavonoids from the fruits of Millettia caerulea. Planta Med. 82(11/12):1096-1104.

 
 

Ren Y, Chen W-L, Lantvit DD, Sass EJ, Shriwas P, Ninh TN, Chai H-B, Zhang X, Soejarto DD, Chen X, Lucas DM, Swanson SM, Burdette JE, Kinghorn AD (2017). Cardiac glycoside constituents of Streblus asper with potential antineoplastic activity. J. Nat. Prod. 80:648-658.
Crossref

 
 

Riley MC (2000). The Traditional Medicine Research Center (TMRC): A potential tool for protecting traditional and tribal medicinal knowledge in Laos. Cult. Surv. Q. 24(4):21-24.

 
 

Saslis-Lagoudakis CH, Savolainen V, Williamson EM, Forest F, Wagstaff SJ, Baral SR, Watson MF, Pendry CA, Hawkins JA (2012). Phylogenies reveal predictive power of traditional medicine in bioprospecting. Proc. Natl. Acad. Sci. U.S.A. 109(39):15835-15840.
Crossref

 
 

Scott JC (2009). The art of not being governed: An anarchist history of upland Southeast Asia. Yale University Press. 

 
 

Shepard GH (2004). A sensory ecology of medicinal plant therapy in two Amazonian societies. Am. Anthropol. 106(2):252-266.
Crossref

 
 

Shoemaker RH (2006). The NCI60 human tumour cell line anticancer drug screen. Nat. Rev. Cancer 6(10):813-823.
Crossref

 
 

Sluis-Cremer N, Koontz D, Bassit L, Hernandez-Santiago BI, Detorio M, Rapp KL, Amblard F, Bondada L, Grier J, Coats SJ, Schinazi RF (2009). Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3′-azido-2′, 3′-dideoxypurine nucleosides. Antimicrob. Agents Chemother. 53(9):3715-3719.
Crossref

 
 

Soejarto DD, Pezzuto JM, Fong HHS, Tan GT, Zhang HJ, Tamez P, Aydogmus Z, Chien NC, Franzblau SG, Gyllenhaal C, Regalado JC, Hung NV, Hoang VD, Hiep NT, Xuan LT, Hai NV, Cuong NM, Bich TQ, Loc PK, Vu BM, Southavong BH, Sydara K, Bouamanivong S, O'Neill MJ, Lewis J, Dietzman G (2002). An international collaborative program to discover new drugs from tropical biodiversity of Vietnam and Laos. Nat. Prod. Sci. 8:1-15.

 
 

Soejarto DD, Fong HHS, Tan GT, Zhang HJ, Ma CY, Franzblau SG, Gyllenhaal C, Riley MC, Kadushin MR, Pezzuto JM, Xuan LT, Hiep NT, Hung NV, Vu BM, Loc PK, Dac LX, Binh LT, Chien NQ, Hai NV, Bich TQ, Cuong NM, Southavong B, Sydara K, Bouamanivong S, Ly HM, Thuy TV, Rose WC, Dietzman GR (2006). Studies on Biodiversity of Vietnam and Laos" 1998-2005: Examining the impact. J. Nat. Prod. 69(Special Issue):473-481.
Crossref

 
 

Soejarto DD, Gyllenhaal C, Kadushin MR, Southavong B, Sydara K, Bouamanivong S, Xaiveu M, Zhang HJ, Rong L, Franzblau SG, Fong HHS, Riley MC, Elkington BG, Waller DP (2012). An ethnobotanical survey of medicinal plants of Laos toward the discovery of bioactive compounds as potential candidates for pharmaceutical development. Pharm. Biol. 50(1):42-60.
Crossref

 
 

Soejarto DD, Elkington BG, Sydara K, Gyllenhaal C, Riley MC, Dietzman GR, Xayvue M, Souliya O, Vanthanouvong M, Southavong B, Kadushin MR, Che C-T (2015). Medicinal plants of Laos: Discoveries, conservation and community engagement – A report submitted to the California Community Foundation. 

 
 

Spjut RW (2005). Relationships between plant folklore and antitumor activity: An historical review. SIDA Contrib. Bot. 21(4):2205-2241.

 
 

Sydara K, Xayvue M, Souliya O, Elkington BG, Soejarto DD (2014). Inventory of medicinal plants of the Lao People's Democratic Republic: A mini review. J. Med. Plants Res. 8(43):1262-1274.

 
 

Zhang H-J, Sydara K, Tan G-T, Ma C, Southavong B, Soejarto DD, Pezzuto JM, Fong HHS (2004). Bioactive constituents from Asparagus cochinchinensis. J. Nat. Prod. 67:194-200.
Crossref

 
 

Zhang HJ, Soejarto DD, Rong L, Fong HHS, Rumschlag-Booms E, inventors (2014). Aryl naphthalide lignans as anti-HIV agents. International Application Number PCT/US2012/048657, filed July 29, 2012 and published June 4, 2014.

 
 

Zhang HJ, Li WF, Fong HHS, Soejarto DD (2016). Discovery of bioactive compounds by the UIC-ICBG drug discovery program in the 18 years since 1998. Molecules 21(11):1448.
Crossref

 
 

Zhang HJ, Rumschlag-Booms E, Guan YF, Wang DY, Liu KL, Li WF, Nguyen VH, Cuong NM, Soejarto DD, Fong HH, Rong L (2017). Potent Inhibitor of Drug-Resistant HIV-1 Strains Identified from the Medicinal Plant Justicia gendarussa. J. Nat. Prod. 80:1798-1807.
Crossref