March 2018

In vitro antiviral activity of Brazilian Cerrado plant extracts against animal and human herpesviruses

The Brazilian savanna known as “Cerrado” is very rich in medicinal plants that are used by the local population for treatment of several illnesses. The herpesvirus is a serious problem worldwide, and affects both animal and human health. This work aimed to study the antiviral activity of eight extracts from plants natives of “Cerrado” region against human (HSV-1), equine (EqHV-1) and swine...

Author(s): Marina A. Padilla, Isabela C. Simoni, Verônica Moreira H. Hoe, Maria Judite B. Fernandes, Clarice W. Arns, Juliana R. Brito and João Henrique G. Lago  

March 2018

Pharmaceutical topical gel containing proanthocyanidin polymers-rich fraction from Stryphnodendron adstringens

The stem bark of Stryphnodendron adstringens, popularly known in Brazil as "barbatimão", has many biological activities, including antifungal activity. Considering the increasing interest of using "barbatimão" extract in the treatment of vaginal candidiasis, the aim of this study was to propose a pharmaceutical topical gel containing a proanthocyanidin polymers-rich fraction for use as...

Author(s): Marco Antonio Costa, Andressa Blainski,  Vanessa Kaplum, Marli Miriam de Souza Lima, Tânia Ueda-Nakamura, Benedito Prado Dias Filho, João Carlos Palazzo de Mello and Celso Vataru Nakamura