July 2013
Effects of pine pollen polysaccharide and its sulfate on the production of ROS in cardiomyocytes
By using the fluorescent probe 2′,7′-di-chlorofluorescein diacetate (DCHF-DA), 2-chloro- 1,3-dibenzothiazoline-cyclohexene (DBZTC) and 2,2,6,6-tetramethyl-1-piperidinoxyl-boron dipyrromethene (TEMPO-BDP) to mark reactive oxygen species (ROS) in cardiomyocytes (H9C2(2-1), the effect of PPM60 and SPPM60 on the production of ROS with laser scanning confocal microscope (LSCM) was detected. The results...
July 2013
Effect of Vernonia amygdalina supplemented diet on selected tissues function in diet-induced obese rats
The present study investigated the impact of Vernonia amygdalina (VA) supplemented diet on blood parameters, and liver and kidney functions in diet-induced obese rats. VA supplemented diet (5 and 15%) was fed for 4 weeks and compared to orlistat (5.14 mg/kg b.w., p.o.), an anti-obesity drug. Full blood counts and some biochemical indices were measured at the end of the study. Platelet count which decreased in...
July 2013
Anti-aging activity of Korean pine (Pinus koraiensis) leaf extracts demonstrated through the induction of mitochondrial biogenesis in mice
Age-related increases in cellular damage and death have been associated with oxidative stress. Mitochondrial biogenesis is likely to be involved in the regulation of cell metabolism and signal transduction. In addition, there is a growing body of evidence suggesting that mitochondrial biogenesis is a key regulator of mitochondrial reactive oxygen species (ROS). Our results demonstrate that Pinus...
July 2013
Antifungal activities of fifteen Southern African medicinal plants against five Fusarium species
In the present study, 35 extracts from 15 different medicinal plants traditionally used in the Venda region for the treatment of fungal related ailments were tested for antifungal activities against five Fusarium spp. including Fusarium oxysporum, Fusarium verticillioides,Fusarium graminearum, Fusarium nygamai and Fusarium proliferatum using the hole plate...
July 2013
Anti-oxidant properties and anti-hemolytic activity of Psidium guajava, Pandanous odorus and Rhinacanthus nasutus
The ethanolic extracts of leaves of Psidium guajava (PG), Pandanous odorus (PO),Rhinacanthus nasutus (RN) contained polyphenolic compounds in the order of PG > RN > PO. All the extracts exhibited 2,2-diphenyl-1-picryhydrazyl (DPPH) and 2,2’-azino-bis 3-ethylbenzothiazoline-6-sulfonic acid (ABTS) radicals scavenging activities. PG showed a marked antioxidant effect whereas PO and RN...
July 2013
Phytochemistry of the genus Selaginella (Selaginellaceae)
The Selaginellaceae family includes the single genus Selaginella, which is found worldwide and comprises approximately 700 to 750 species. A number of species have been traditionally used for medicinal purposes in the whole world, and the phytochemistry of some has been investigated. For this review, the search was carried out using Web of Sciences, Chemical Abstracts and the data bank NAPRALERT (acronym for...
July 2013
Genetic diversity in Aloe vera accessions from Iran based on agro-morphological, phytochemical and random amplified polymorphic DNA (RAPD) markers
Aloe vera is highly valued for anthraquinones compounds found in their leaves. The main objectives of the present study were to (1) evaluate phenotypic and molecular diversity among Iranian Aloe accessions; (2) compare Aloin content among accessions collected from different ecological areas; (3) determine correlations between Aloin content and morphological traits; and (4) estimate the broad-sense heritability...
July 2013
Optimization study for the extraction of phenolics-rich silymarin from Silbum marianum
Crude extract of milk thistle (Silbum marianum) seeds have been used for centuries as an herbal treatment for liver diseases. The seeds of milk thistle are usually pretreated with organic solvent to defat the seed prior to flavonolignan extraction. The current work aims to obtain maximum yield of phenolics-rich silymarin extract. The tested parameters were seed defatting, temperature, extraction time, solvent type...
July 2013
Antibacterial, antioxidant and phytochemical investigation of Thuja orientalis leaves
In the present study, leaves of Thuja orientalis were powdered and extracted by soxhlet extractor in two solvent systems that is, (E1) ethyl acetate: chloroform: ethanol (40: 30: 30) and (E2) methanol: distilled water (70:30). This study conferred the screening of phytochemical constituents, antioxidant activity and antibacterial activity of crude E1 and E2extract and its fractions. Antioxidant activity...
July 2013
In vitro antimicrobial activity of the chemical constituents of Cirsium arvense (L). Scop
Anti-bacterial and anti-fungal activities of the isolated constituents from Cirsium arvense were evaluated. These five compounds namely α-tocopherol, 9, 12, 15-octadecatrienoic acid, tracin, hispidulin and luteolin were isolated from the ethyl acetate soluble fraction of the methanolic extract of the plant. Their structures have been identified by electrochemical impedance spectroscopy (EIS), high resolution...
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