April 2023

Phytochemical screening, anti-inflammatory and immunomodulatory activities of Acanthospermum hispidum and Croton zambesicus collected in the Republic of Benin

This study aims to characterize chemical groups of metabolites in extracts of Acanthospermum hispidum and Croton zambesicus, and to evaluate their anti-inflammatory activities and their immunomodulatory effect on two pro-inflammatory cytokines (TNFα and IL6). The phytochemical screening was done on the powders of both plants by staining and precipitation reactions. Anti-inflammatory activity was performed in vivo...

Author(s): Paulin Kpodji, Gatien Lokossou, Victorien Dougnon, Phénix Assogba, Alidehou Jerrold Agbankpé, Esther Déguénon, Gérardo Agbaka, Expédit Yéhouénou, Tatiana Hountohotègbè, Jean-Robert Klotoé, Kévin Sintondji and Lamine Baba-Moussa