June 2011

Effect of a natural antioxidant fruit – tomatoes (Lycoperscion esculentium) as a potent nephro-protective agent in lead induced nephrotoxicity in rat

The toxicity of lead (Pb) to the kidney amongst other organs is not in doubt, in that various devices and interventions, aimed at mitigating its toxic effect, have also been described. Effect of lycopene (the active constituent of tomatoes) as a natural antioxidant in modulating Pb toxicity and its attendant reduction of reduced glutathione (GSH) levels inPb poisoned kidney tissue of Wister rats is the...

Author(s): Omotosho Ishiaq, Adeagbo A. G. and Henshaw Nta

June 2011

Exposure to smoke extract of Datura stramonium leaf: Some of its effects on the heart, liver, lungs, kidneys and testes of male Sprague Dawley rats

Smoking has been recognized as a significant contributor to mortality. The aim of this study was to evaluate some of the toxic effects of smoke extract of Datura stramonium leaf on the heart, liver, kidneys and testes of male Sprague Dawley rats. A total of ten male Sprague Dawley rats weighing between 100 and 120 g were used for this study. The animals were randomly assigned into two (2) groups; A and B....

Author(s): Adekomi D. A., Musa A. A., Tijani A. A., Adeniyi T. D. and Usman B.