Journal of
Toxicology and Environmental Health Sciences

  • Abbreviation: J. Toxicol. Environ. Health Sci.
  • Language: English
  • ISSN: 2006-9820
  • DOI: 10.5897/JTEHS
  • Start Year: 2009
  • Published Articles: 218

Full Length Research Paper

Novel expression of the biomarker, Nε-hexanoyl lysine in gibberellic acid induced bone toxicity in adult albino rats

Dalia M. Amin
  • Dalia M. Amin
  • Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Zagazig University, Egypt.
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Aisha A. Abohashem
  • Aisha A. Abohashem
  • Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Zagazig University, Egypt.
  • Google Scholar
Ola A. Harb
  • Ola A. Harb
  • Department of Pathology, Faculty of Medicine, Zagazig University, Egypt.
  • Google Scholar
Walaa M. Sarhan
  • Walaa M. Sarhan
  • Department of Medical Biochemistry and molecular biology, Faculty of Medicine, Zagazig University, Egypt.
  • Google Scholar
Marwa A. Shabana
  • Marwa A. Shabana
  • Department of Clinical Pathology, Faculty of Medicine, Zagazig University, Egypt.
  • Google Scholar


  •  Received: 24 February 2018
  •  Accepted: 10 April 2018
  •  Published: 30 April 2018

References

Abou-Eisha A (2001). Evaluation of cytogenetic and DNA damage induced by Gibberlic acid. Toxicol . Vitro 20(5):601-607.
Crossref

 

Aebi H (1984). Catalase in vitro. Methods Enzymol. 105:121-126.
Crossref

 

Bai XC, Lu D, Bai J, Zheng H, Ke ZY, Li XM, Luo SQ (2004). Oxidative stress inhibits osteoblastic differentiation of bone cells by ERK and NF-κB. Biochem. Biophys. Res. Commun. 314(1):197-207
Crossref

 

Beauchamp C, Fridovich I (1971). Superoxide dismutase: improved assays and an assay applicable to acrylamide gels. Anal. Biochem. 144(1):276-287.
Crossref

 

Biaocon M (2004). Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol. 186:421-431.

 

Ceconi C, Boraso A, Cargnoni A, Ferrari R (2003). Oxidative stress in cardiovascular disease: myth or fact?. Arch. Biochem. Biophys. 420(2):217-221.
Crossref

 

Celik I, Tuluce Y (2007). Evalution of toxicity of abcisic acid and gibberellic acid in rats: 50 days drinking water study. J. Enzym. Inhib. Med. Chem. 22(2):219-226.
Crossref

 

Celik I, Turker M, Tuluce Y (2007). Abcisic acid and gibberellic acid cause increased lipid peroxidation and fluctuated antioxidant defense systems of various tissues in rats. J. hazard. Mater. 148(3):623-629.
Crossref

 

Cuschieri A, Backer P (1977). Introduction to Research in Medical Sciences(1st ed.). By: Cuschieri, A. and Backer, P.P. (eds.).Churchill Livingstone, Edinburgh. pp. 112-120.

 

Draper HH, Hadley M (1990). Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol. 86:421-431.
Crossref

 

Ellman GL (1959). Tissue sulfhydryl groups. Arch. Biochem. Biophys. 82:70-77.
Crossref

 

Fetoui H, Mahjoubi-Samet A, Jammousi K, Ellouze F, Guermazi F, Zeghal N (2006). Energy restriction in pregnant and lactating rats lowers bone mass of their progeny. Nutr. Res. 26(8):421-426.
Crossref

 

Flohe A, Günzler WA (1984). Assays of glutathione peroxidase. Methods Enzymol. 105:114-121.
Crossref

 

Ha H, Kwak HB, Lee SW, Jin HM, Kim HM, Kim HH, Lee ZH (2004). Reactive oxygen species mediate RANK signaling in osteoclasts. Exper. Cell Res. 301(2):119-127.
Crossref

 

Hassab-Elnabi SE, Sallam FA (2002). The protective effect of ellagic acid against themutagenic potential of Berelex® in human lymphocyte cultures. J. Egypt. Germ. Soc. Zool. 37(C):77-98.

 

Ichiseki T, Kaneuji A, Ueda Y, Nakagawa S, Mikami T, Fukui K, Matsumoto T (2011). Osteonecrosis development in a novel rat model characterized by a single application of oxidative stress. Arthritis Rheumatol. 63(7):2138-2141.
Crossref

 

Institute of Laboratory Animal Resources (1996). Guide for the Care and Use of Laboratory Animals. (7thed.). National Academy Press. P 125.

 

Kamel KI, Elkomy AE, El-Sbeiy ME (2009).The Androgenic Action of Gibberellic Acid (GA3) on Reproductive Performance of New Zealand White Rabbit Bucks. 

View

 

Lean J, Kirstein B, Urry Z, Chambers T, Fuller K (2004). Thioredoxin-1 mediates osteoclast stimulation by reactive oxygen species. Biochem. Biophys. Res. Commun. 321:845-850.
Crossref

 

Mahjoubi-Samet A, Fetoui H, Boujelben G, Jamoussi K, Ammar E, Ellouze F, Guermazi F, Zeghal N (2005). Effects of dimethoate on bone maturation of young rats during the suckling period. Pestic. Biochemi. Physiol. 83(2-3):132-139.
Crossref

 

Martinez Salgodo C, Lopez Hernandez FJ, Lopez Novao JM (2017). Reviews in Mechanistic Toxicology, Glomeruler nephrotoxicity of amino glycosides. Toxicol. Appl. Pharmacol. 132(7):220-227.

 

Mody N, Parhami F, Sarafian TA, Demer LL (2001). Oxidative stress modulates osteoblastic differentiation of vascular and bone cells. Free Radic. Biol. 31:509-516.
Crossref

 

Nemzek JA, Bolgos GL, Williams BA, Remick DG (2001). Differences in normal values for murine white blood cell counts and other hematological parameters based on sampling site. Inflamm. Res. 50(10):523-527.
Crossref

 

Ohn JA, Blogg CD, Murray FJ (2017). Teratogenic effects of the plant hormone indole-3-acetic acid in mice and rats. Teratol. 19(3):321-324.

 

Ramajayam G, Sridhar M, Karthikeyan S, Lavanya R, Veni S, Vignesh RC, Ilangovan R, Djody SS, Gopalakrishnan V, Arunakaran J, Srinivasan N (2007). Effects of Aroclor 1254 on femoral bone metabolism in adult male Wistar rats. Toxicology 241(3):99-105.
Crossref

 

Ramwant G, Chakrabarty S (2017). Gibberellic acid in plant. Plant. Signal. Behav. 1:8-9. 

View

 

Rommer PS, Dudesek A, Zettl U (2004). Monoclonal antibodies in treatment of multiple sclerosis. Clin. Exp. Immunol. 175(3):373-384.
Crossref

 

Ross JJ, Weston DE, Davidson SE, Reid JB (2011). Plant hormone interactions: how complex are they? Physiol. Plant. 141(4):299-309.
Crossref

 

Satarug S, Baker JR, Urbenjapol S (2004). A global perspective on cadimium, pollution and toxicity in non-occupationally exposed population. Toxicol. Lett. 137:65-83.
Crossref

 

Semler DE (1992). The rat toxicology. In: Animal Models in Toxicology. (2nd ed.). By: Gad, S.C. and Chengelis, C.P. (eds.). Marcl Dekker, New York and Hong Kong. Chap: 2. pp. 21-75.

 

Sripaiboonkij P, Phanprasit W, Jaakkola MS (2016). Respiratory effects of occupational exposures in a milk powder factory. Eur. Respir. J. 31(4):807-814.
Crossref

 

Troudi A, Mahjoubi-Samet A, Zeghal N (2010). Hepatotoxicity induced by gibberellic acid in adult rats and their progeny. Exp. Toxicol. Pathol. 6:10.
Crossref

 

Ustun H, Tecimer T, Ozmen M (1992). Effects of gibberellic acid and benzoprenin on mice. Hispathologic Rev. Ank. Pathol. Bult. 9:36-40.

 

Yavas A O¨zmen M, Topcuoglu FS (2017). Analysis of gibberellic acid, abscisic acid, indole-3-acetic acid and zeatin from selected tissues of albino mice. Toxicol. Environ. Chem. 59:251-260.
Crossref