March 2024

Evaluation of Benz[A]anthracene-induced pulmonary toxicity in Rattus norvegicus

Benz[a]anthracene is a polycyclic aromatic hydrocarbon (PAH) commonly found in the environment, capable of inducing an inflammatory response that may lead to pulmonary toxicity. Due to a lack of knowledge regarding the signs and pathological damages caused by benz[a]anthracene toxicity, there is a need to investigate its effects in a rat model. The determination of the median lethal dose (LD50) involved nine rats using...

Author(s): Oladipo Miriam Oluchi, Nwankwo Henry Chukwuebuka, Orbunde, David Kparevzua, Achanya Wisdom Daniel, Upev Vincent Aondohemba, Imotor Isaac Ieren, Bosha Joel A, Saganuwan Alhaji Saganuwan and Onyeyili Patrick Azubuike