Full Length Research Paper
Although it is generally accepted that modified ultrafiltration (MUF) improves operative outcomes in pediatric cardiac surgery, the evidence for this remains equivocal. Previous meta-analyses have been affected by significant patient and method heterogeneity. Google Scholar and PUBMED were searched between January 1st 1966 and May 31st 2022. We conducted a meta-analysis after pragmatically minimising patient and method heterogeneity. There were 631 patients (314 MUF vs 317 ‘No MUF’) in the the mortality analysis and 258 patients (129 MUF vs 129 ‘No MUF’) in the ‘duration-of-ventilation’ (DOV) and ‘length-of-hospital stay’ (LOHS) analyses. There was no significant difference in operative mortality, DOV and LOHS. There is no evidence that MUF improves these operative outcomes in paediatric cardiac surgery.
Key words: Modified ultrafiltration, pediatric, cardiac surgery.
Copyright © 2023 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0