Full Length Research Paper
Abstract
The antidenaturation and antioxidant properties of Spondias mombin Linn (Anacardiaceae) methanol leaf extract (SMC) and fractions prepared from it were evaluated in this study. SMC and its fractions: ether (SME), saponin-rich (SMS) and flavonoid-rich (SMF) were phytochemically screened and evaluated for total antioxidant activity (TAA), ability to inhibit deoxyribose degradation (DEO), lipid peroxidation inhibitory activity (LPIA), 2,2 - diphenyl-1-picryl hydrazyl scavenging activity, ability to chelate ferrous ions and protein denaturation inhibitory activity (PRO). The antioxidant and antidenaturation activities were in the order SME > SMF > SMC > SMS. TAA strongly correlated with DEO, LPIA and PRO. The results indicate that S. mombin contains a diverse array of phytochemicals with potent antioxidant and bio-preservative properties which can serve as candidates for food preservation and drug development.
Key words: Spondias mombin, phytoconstituents, antioxidant activity, protein denaturation.
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