African Journal of
Biochemistry Research

  • Abbreviation: Afr. J. Biochem. Res.
  • Language: English
  • ISSN: 1996-0778
  • DOI: 10.5897/AJBR
  • Start Year: 2007
  • Published Articles: 404

Full Length Research Paper

Serum lipid profile based on the prandial state among adult subjects

Moutawakilou Gomina
  • Moutawakilou Gomina
  • Department of Biochemistry, Faculty of Medicine, University of Parakou, Benin.
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Corinne Tchegnonsi Tognon
  • Corinne Tchegnonsi Tognon
  • Department of Biochemistry, Faculty of Medicine, University of Parakou, Benin.
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Tarik Salifou
  • Tarik Salifou
  • Department of Biochemistry, Faculty of Medicine, University of Parakou, Benin.
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Gilbert Djidonou
  • Gilbert Djidonou
  • Laboratory of Biochemistry, Parakou Teaching Hopital, Parakou, Benin.
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Stanislas Zinsou
  • Stanislas Zinsou
  • Laboratory of Biochemistry, Parakou Teaching Hopital, Parakou, Benin.
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  •  Received: 20 February 2021
  •  Accepted: 22 July 2021
  •  Published: 31 July 2021

Abstract

This study was aimed to access the variations in serum lipid parameters based on the prandial state of adult patients. Through a cross-sectional descriptive and analytical study conducted in Parakou (Benin), from February 1 to May 1, 2020, 100 adult subjects (average age 31.21±12.36 years) were selected with systematic census. After ethical advice, a first sample was taken on empty-bellied adult subjects. Then, three additional samples were respectively taken two hours, four hours, and six hours after these subjects had eaten a meal of their choice. Serum lipid parameters were measured through enzymatic colorimetric methods. The average values of fasting lipid parameters in g/L were: Total cholesterol (1.48±0.35), HDL cholesterol (0.49±0.14), LDL cholesterol (0.84±0.36) and triglycerides (0.63±0.34). The comparison of the fasting and postprandial lipid parameters values is presented as follow: Triglyceridemia was significantly higher 2 h (P=0.000) and 4 h after meal (P=0.001). Only one type of food consumed was associated with mixed hyperlipidemia at six hours postprandial state (P=0.022).  It may therefore be concluded that consumed foods do not cause most dyslipidemias 6 h in the postprandial state. During the screening for dyslipidemias in adults, the lipid profile can therefore be measured after six hours postprandial state.

 

Key words:  Lipid profile, fasting, prandial state, adults.