African Journal of
Biochemistry Research

  • Abbreviation: Afr. J. Biochem. Res.
  • Language: English
  • ISSN: 1996-0778
  • DOI: 10.5897/AJBR
  • Start Year: 2007
  • Published Articles: 425

Full Length Research Paper

Effect of essential oil of the leaves of Eucalyptus globulus on heamatological parameters of wistar rats

OYESOMI, Tajudeen Oyesina1*, AJAO, Moyosore Salihu2, OLAYAKI, luquman Aribidesi4and ADEKOMI, Damilare Adedayo3
1Department of Anatomy, Kampala International University, Dar es Salaam, Tanzania. 2School of Anatomical Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. 3Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin, Kwara State. 4Department of Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin, Kwara State.
Email: [email protected], [email protected]

  •  Accepted: 09 January 2012
  •  Published: 29 February 2012

Abstract

The study was designed to evaluate the effect of essential oil extract of Eucalyptus globulus on haematological parameters of wistar rats. Twenty-five adult wistar rats weighing between 80 to 130 g were used. The rats were divided into five groups; with group one as the control group. Increasing doses (12.5, 25.0, 50.0, 72.5 mg/ml) of the extract were administered orally daily to the other four groups for a period of four weeks. The animals were sacrificed and the blood collected for haematological parameters using automated haematological analyzer K-X-21 machine. The results indicate significant increases in level of Haemoglobin (Hb), White Blood Cell (WBC), and Red Blood Cell (RBC) but a decrease in the levels of the Mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC). The study confirmed that extract oil of eucalyptus globulus have some significant effects on haematological parameters of the wistar rats and these effects are dose dependent.

 

Key words: Eucalyptus globulus, oil extract, haematological parameters, wistar rats.

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