Profile of Biochemical Markers of Malnutrition and Iron Deficiency in Chronic Kidney Disease Patients Hemodialyzed at Souro Sanou University Hospital Undernutrition and iron deficiency in hemodialysis patients are associated with a high risk of mortality. The aim of this study was to evaluate the profile of biochemical markers of protein undernutrition and iron deficiency in hemodialysis patients. This was a descriptive cross-sectional study with a data collection period from 1er January 2022 to 28 February 2022. The study concerned hemodialysis patients not presenting with an inflammatory syndrome (CRP<5mg/L) at the SS-UH. The parameters measured in the biochemistry laboratory were CRP, prealbumin, albumin, alpha-1- glycoprotein, haptoglobin, transferrin, ferritin, serum iron and transferrin saturation coefficient (TSC). A total of 41 hemodialysis patients were included in the study. The mean age was 42.93±12.21 years. The patients were predominantly male, with a sex ratio (M/F) of 1.56. Glomerular filtration rate was <15 ml/min/1.73 m2 in 85.37% of patients. All biochemical markers were impaired. However, the major disorders concerned 2.44% hypoalbuminemia, 2.44% hypoprealbuminemia, 73.17% hyposideremia, 85% hypotransferrinemia and a drop in TSC in 39.03% of patients. The incidence of undernutrition was 4.88%, while iron deficiency was present in 39.03% of patients. The management of inflammation, undernutrition and iron deficiency should be integrated into the overall therapeutic strategy for CKD hemodialysis patients.

Keywords: Hemodialysis, malnutrition, iron deficiency, inflammation.