January 2009

Regenerative action of Cochlospermum tinctorium aqueous root extract on experimentally induced hepatic damage in rats

  The hepatoprotective effect of aqueous root extract of Cochlospermum tinctoriumon carbon tetrachloride (CCl4) on induced hepatic damage in rats was reported. The present study examined the curative action of the plant extract on experimentally induced hepatic damage in rats. Wistar rats were divided into normal control, induction control, extract and prednisolone treated groups. Hepatotoxicity was...

Author(s): Etuk E. U., Francis U. U. and Garba I.

January 2009

Efficacy of Dissotis rotundifolia on Trypanosoma brucei brucei infection in rats

  The therapeutic potential of the crude extract of Dissotis rotundifolia was   investigated in rats infected with Trypanosoma b. brucei. Animals were treated orally or intraperitoneally at 200, 600 and 800 mg/kg body weight. At 800 mg/kg, parasitemia was reduced by 66.7 and 78.4% after oral and intraperitoneal administration respectively. In vitro exposure of blood forms to...

Author(s): Abdullahi Mann, Evans C. Egwim, Barnabas Banji, Nda-Umar Abdukadir, Mohammed Gbate and J. T. Ekanem