African Journal of
Cellular Pathology

OFFICIAL PUBLICATION OF THE SOCIETY FOR CELLULAR PATHOLOGY SCIENTISTS OF NIGERIA
  • Abbreviation: Afr. J. Cell. Path
  • Language: English
  • ISSN: 2449-0776
  • DOI: 10.5897/AJCPath
  • Start Year: 2013
  • Published Articles: 107

Full Length Research Paper

Assessment of the effect of post-natal lead exposure on the hippocampus of developing Wistar rats

Oluwasegun Davis Olatomide
  • Oluwasegun Davis Olatomide
  • Neuroscience Unit, Department of Human Anatomy, Faculty of Basic Medical Sciences, College of Medical Sciences, Ahmadu Bello University, Zaria, Nigeria.
  • Google Scholar
Sunday Samuel Adebisi
  • Sunday Samuel Adebisi
  • Neuroscience Unit, Department of Human Anatomy, Faculty of Basic Medical Sciences, College of Medical Sciences, Ahmadu Bello University, Zaria, Nigeria.
  • Google Scholar
Sunday Abraham Musa
  • Sunday Abraham Musa
  • Neuroscience Unit, Department of Human Anatomy, Faculty of Basic Medical Sciences, College of Medical Sciences, Ahmadu Bello University, Zaria, Nigeria.
  • Google Scholar


  •  Received: 18 March 2019
  •  Accepted: 22 May 2019
  •  Published: 31 December 2019

References

Ab Latif W, Anjum A, Jawed AU (2015). Lead toxicity: a review. Interdisciplinary Toxicology 8(2):55-64.
Crossref

 

Abbas ZA (2015). The possible protective role of vitamin E on the joined neurobehavioural effects of lead toxicity and noise stress in rats. Journal of International Academic Research for Multidisciplinary 3(4):256-268.

 

Abdulrazzaq MA, Mohammed MH, Wahid AH, Yusof MS, Mohammed AR (2016). Prophylactic effect of Nigella sativa against lead acetate induced changes in spermiogram, reproductive hormones and gonadal histology of rats. Veterinary World 9(6):660-671.

 

Adebisi SS (2008). The toxicity of artesunate on bone developments: the Wistar rat animal model of malaria treatment. The Internet Journal of Parasitic Diseases 4(1):1-8.
Crossref

 

Adekomi DA, Adewole OS, Tijani AA, Adeniyi TD (2017). Lead induces inflammation and neurodegenerative changes in the rat medial prefrontal cortex. Anatomy 11(2):79-86.
Crossref

 

Adekomi DA, Adewole OS, Tijani AA, Adeniyi TD (2017). Lead induces inflammation and neurodegenerative changes in the rat medial prefrontal cortex. Anatomy 11(2):79-86.
Crossref

 

Alyaa MM, Ameera SA, Muddanna SR, Narayana K (2015). Gestational lead exposure induces developmental abnormalities and up-regulates apoptosis of fetal cerebellar cells in rats. Drug and Chemical Toxicology 38(1):73-83.
Crossref

 

Aprioku JS, Siminialayi IM (2013). Maternal lead exposure and pregnancy outcome in Wistar albino rats. Journal of Toxicology and Environmental Health Sciences 5(10):185-193.
Crossref

 

Arif TJ, Mudsser A, Kehkashan S, Arif A, Inho C, Qazi M, Rizwanul H (2015). Heavy Metals and Human Health: Mechanistic Insight into Toxicity and Counter Defense System of Antioxidants. International Journal of Molecular Sciences 16:29592-29630.
Crossref

 

ATSDR (2017). Agency for Toxic Substances and Disease Registry. Toxicological Profile for Lead. Update. U.S. Department of Health and Human Services. Public Health Service 1-185.

 

Bellinger DC (2004). Lead. Pediatrics 113(4):1016-1022. 

View

 

Burger J, Gochfeld M, Jeitner C (2011). Locational differences in mercury and selenium levels in 19 species of saltwater fish from New Jersey. Journal of Toxicology and Environmental Health part A 74(13):863-874.
Crossref

 

Clark CS, Adebamowo CA, Adebamowo EO, Agbede OA, Chen CK, El-Safty A, Menrath W, Rampal KG, Roda SM, Shinde RM, Sridhar MKC, Succop P, Thuppil V, Yu J, Zakaria Y (2009). Lead levels in new enamel household paints from Asia, Africa and South America. Environmental Research 109:930-936.
Crossref

 

Corpas I, Castillo M, Marquina D, Benito MJ (2002). Lead intoxication in gestational and lactation periods alters the development of male reproductive organs. Ecotoxicology and Environmental Safety 53:259-266.
Crossref

 

Du Y, Ge MM, Xue W, Yang QQ, Wang S, Xu Y, Hui-Li W (2015). Chronic Lead Exposure and Mixed Factors of Gender×Age×Brain Regions Interactions on Dendrite Growth, Spine Maturity and NDR Kinase. PLoS ONE 10(9):e0138112.
Crossref

 

El Sayed AM, Ahmed NF, Rania AS, Eman MN (2015). Anatomical and Histological Study of the Effect of Lead on Hepatocytes of Albino Rats. International Journal of Biomedical Materials Research 3(4):34-45.
Crossref

 

Ettinger AS, Roy A, Amarasiriwardena CJ, Smith D, Lupoli N, Mercado-García N, Lamadrid-Figueroa H, Tellez-Rojo MM, Hu H, Hernández-Avila M (2014). Maternal Blood, Plasma, and Breast Milk Lead: Lactational Transfer and Contribution to Infant Exposure. Environmental Health Perspectives 122(1):87-92.
Crossref

 

Fedorenko GM, Uzdensky AB (2010). Nissl substance and cellular structures involved in the intraneuronal and neuroglial transport in the crayfish stretch receptor. Microscopy: Science, Technology, Applications and Education. Méndez-Vilas A, Díaz J (Eds.) pp. 299- 306.

 

Flora G, Gupta D, Tiwari A (2012). Toxicity of lead: A review with recent updates. Interdisciplinary Toxicology 5(2):47-58.
Crossref

 

Gorini F, Chiappa E, Gargani L, Picano E (2014). Potential effects of environmental chemical contamination in congenital heart disease. Pediatric Cardiology 35(4):559-568.
Crossref

 

Hamza GA, Ibegbu AO, Buraimoh AA (2017). Evaluation of the Effects of Aqueous Garlic Extract on Lead-Induced Changes on Cerebellum of Wistar rats. African Journal of Cellular Pathology 8:9-14.
Crossref

 

Haouas Z, Sallem A, Zidi I, Hichri H, Mzali I, Mehdi M (2014). Hepatotoxic Effects of lead acetate in rats: histopathological and cytotoxic studies. Journal of Cytology and Histology 5(5):1-6.

 

Kang JK, Donggeun S, Kang JK, Sang-Yoon N, Hae-Joon K, Lee E (2004). Effects of Lead Exposure on the Expression of Phospholipid Hydroperoxidase Glutathione Peroxidase mRNA in the Rat Brain. Toxicological Sciences 82:228-236.
Crossref

 

Kasten-Jolly J, Bolivar VJ, Lawrence DA, Pabello N (2012). Developmental lead effects on behavior and brain gene expression in male and female BALB/cAnNTac mice. Neurotoxicology 33:1005-1020.
Crossref

 

La-Llave-León O, Pacheco MS, Martínez SE, Rodríguez EE, Francisco X, Castellanos J, Carrillo AS, Quiñones AM, Alanís FV, Vargas GG, Hernández MM, Sustaita JD (2016). The relationship between blood lead levels and occupational exposure in a pregnant population. BMC Public 16:1231. Lewis MW, Pitts DK (2004). Inorganic lead exposure in the rat activates striatal cFOS expression at lower blood levels and inhibits amphetamine-induced cFOS expression at higher blood levels. Journal of Pharmacology and Experimental Therapeutics 310(2):815-820.
Crossref

 

Lindquist DM, Beckwith T, Cecil KM, Sánchez-Martín FJ, Landero-Figueroa J, Puga A (2015). Prenatal and early postnatal lead exposure in mice: neuroimaging findings. Quantitative Imaging in Medicine and Surgery 4:511-518.

 

Marcondes FK, Bianchi FJ, Tanno AP (2002). Determination of the estrous cycle phases of rats: Some helpful considerations. Brazilian Journal of Biology 62(4a):609-614.
Crossref

 

McClintock MK (1978). Synchronizing Ovarian and Birth Cycles by Female Pheromones. Chemical Signals in Vertebrates 3:159-178.
Crossref

 

Omayma KH, Ayman MM, Nadra K (2011). Effect of antioxidants on hippocampal structure in male albino rats exposed to lead toxicity: histological and biochemical study. The Egyptian Journal of Histology 34:808-817.
Crossref

 

Rahman A, Khan KM, Al-Khaledi G, Khan I, Sreeja A (2012). Early postnatal lead exposure induces tau phosphorylation in the brain of young rats. Acta Biologica Hungarica 63(4):411-425.
Crossref

 

Rai A, Maurya SK, Khare P, Srivastava A, Bandyopadhyay S (2010). Characterization of developmental neurotoxicity of As, Cd, and Pb mixture: synergistic action of metal mixture in glial and neuronal functions. Toxicology of Science 118:586-601.
Crossref

 

Saeed AA (2016). Hematobiochemical changes induced by lead intoxication in male and female albino mice. National Journal of Physiology, Pharmacy and Pharmacology 6(1):46-51.
Crossref

 

Sanders T, Liu Y, Buchner V, Tchounwou PB (2009). Neurotoxic Effects and Biomarkers of Lead Exposure: A Review. Review on Environmental Health 24(1):15-45.
Crossref

 

Sansar W, Ahboucha S, Bouyata M, Gamrani H (2012). Effects of chronic lead intoxication on rat serotoninergic system and anxiety behavior. Acta Histochemica 114(1):41-45.
Crossref

 

Sharafi K, Fattahi N, Pirsaheb M, Yarmohamadi H, Fazlzadeh-Davil M (2015). Trace determination of lead in lipsticks and hair dyes using microwave‐assisted dispersive liquid‐liquid microextraction and graphite furnace atomic absorption spectrometry. International Journal of Cosmetic Science 37(5):489-495.
Crossref

 

Sobin C, Flores MGM, Parisie N, Schaube T, Cervantesa M, Rodrigo XA (2013). Microglial disruption in young mice with early chronic lead exposure. Toxicology Letters 220(1):44-52.
Crossref

 

Sujatha K, Srilatha C, Anjaneyulu Y, Amaravathi P (2011). Lead acetate induced neurotoxicity in Wistar albino rats: A pathological, immunological, and ultrastructural studies. The Journal of Pharmaceutical and Biological Science 2:459-462.

 

Syed ZN (2015). A Comparative Study of the Histological Changes in Cerebral Cortex, Hippocampus, Cerebellum, Pons & Medulla of the Albino rat due to Lead Toxicity. International Journal of Anatomy and Research 3(2):1173-1178.
Crossref

 

Terry JAV (2009). Spatial Navigation (Water Maze) Tasks. In: Buccausco JJ. Methods of Behaviour Analysis in Neuroscience. CRC Press, Boca Raton pp. 13.1-13.4.

 

Wang Q, Luo W, Zhang W, Liu M, Song H, Chen J (2011). Involvement of DMT1+IRE in the transport of lead in an in vitro BBB model. Toxicology in Vitro 25:991-998.
Crossref

 

Wellington D, Mikaelian I, Singer L (2013). Comparison of Ketamine-Xylazine and Ketamine-Dexmedetomidine Anesthesia and Intraperitoneal Tolerance in Rats. Journal of the American Association for Laboratory Animal Science 52:481-487.

 

Zaheer A, Muhammad ZI, Amir AS (2013). Lead-Induced Reduction in Body and Kidney Weight of Wistar Albino Rats Ameliorated by Ginkgo biloba Extract (EGb 761). Biochemical Physiology 2(2):2.